Night vision--Genetic aspects; Vision disorders--Genetic aspects
Mutations in the NYX gene, encoding the novel protein nyctalopin, cause human congenital stationary night blindness type 1 (CSNB1). CSNB1 is an X-linked recessive condition and is identified by a loss of the electroretinogram (ERG) b-wave while the...
This research was performed to establish the feasibility of using Direct Metal Deposition (DMD) technology to deposit nickel powder to a nickel substrate. The substrate is electrodeposited pure nickel, and the material to be deposited is Metco...
In the retina, the receptive fields (RFs) of most neurons are comprised of an excitatory center and a suppressive surround. Retinal ganglion cell (RGC) RF center excitatory input arises from bipolar cell (BC) inputs, while their surround arises...
Genes in folate metabolizing pathway are responsible for modulating key enzymes in folate metabolisms necessary for DNA synthesis and repair and influence DNA methylation. Irregularity in DNA methylation may modify tumor phenotype response to...
This thesis is a methodological analysis of fire locations in Canadian provinces
from 2001 to 2010. The research presented in this thesis highlights the dominant fire
types for each province. Accurately locating active fires and burned area is...
Marginal inference for waiting times in multi-stage time-to-event models is complicated by right censoring of observations as well as the prior history of events in the model. In general, complications arise due to the evolution of the censoring...
Electronic communication is gradually becoming a larger part of today's
society. This type of communication not only encompasses ways people stay in
touch, but also how people manage or share their personal data. As this type of
communication...
This research project describes the application of a master/slave configuration of processors to study a comparison of alternative material handling configurations for automated manufacturing. Such a study usually requires a large number of...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There are significant portions missing from the bottom of each page of this issue.
“The Erechtheum seen from the west, as it might have appeared at the beginning of the fourth century BC. A sacrificial procession with a lamb for the sacrifice is approaching the sanctuary of Athena Polias.” (p.77); "[...] in 420 BC the...
Background: When rat salivary gland cells are cultured in vitro, they dedifferentiate within 24 h. Hypothesis: Growth factors will prevent de-differentiation of primary cultures of parotid gland cells, and they will induce differentiation of ParC5...
Heart failure is the most frequent cause of mortality in western countries. Currently, there is no cure treatment for heart failure and the long term survival rate following heart failure is poor, with one third of patients dying within a year of...
Speech intelligibility has been found to improve with prior exposure to a reverberant room environment. It is believed that perceptual mechanisms help maintain accurate speech perception under these adverse conditions. Potential factors underlying...
Bcl-2 proteins are major regulators of cellular responses to various apoptotic stimuli. Among them, overexpression of the anti-apoptotic BcI-2 protein BcI-xL modulates organelle-specific apoptotic pathways. To understand the mechanisms by which...
Integrated circuits--Design and construction; Integrated circuits industry--Technological innovations
Lithographic processes for printing device structures on integrated circuits plays a major role in the semiconductor industry. This project aims at designing and fabricating a programmable mask for a direct write lithography system which can...
Indians of North America--British Columbia; Literacy--British Columbia--Case studies
This dissertation examines the literacy practices of a group of First Nations women who live in British Columbia and whose jobs entail the production and dissemination of texts which reflect the local, Carrier, culture. In this qualitative study of...
Rising concerns about dependency on fossil fuels in the 21st century has sparked a growth in research for renewable energy sources. One renewable energy production process of interest is the reduction of cellulose into fermentable sugars by means...
Law and legislation--Kentucky; Law and legislation--Virginia
Littell's Statute Law of Kentucky, published from 1809-1819, has the first critically edited compilation of Kentucky statutes. It has long been recognized by lawyers as one of the founding documents of state law and by historians of early Kentucky...
