Bcl-2 proteins are major regulators of cellular responses to various apoptotic stimuli. Among them, overexpression of the anti-apoptotic BcI-2 protein BcI-xL modulates organelle-specific apoptotic pathways. To understand the mechanisms by which...
Here, I address the function of the carboxy-terminal hydrophobic helix of the pro-apoptotic protein Bax. There has been considerable controversy as to whether this sequence is required for the targeting and insertion of Bax into the mitochondrial...
A careful perusal of Shakespeare’s works leads to one outstanding conclusion. Shakespeare was preeminently interested in words, as such. His every play shows a painstaking attention to words in their various shades of meaning. It is our interest...
Feminism in literature; Self-perception in literature; Women in literature; Chen, Ran, 1962-; Tan, Amy
With increasing cross-cultural infiltrations and accelerated interflows among people of all nationalities in this globalized world, the focus of comparative literature has experienced a shift from traditional Eurocentric cannons to a broader space...
Prostate cancer (PCA) development may be influenced by genetic variations within oxidative stress response (OSR) related mechanisms, such as antioxidation (e.g.,
carcinogen metabolism/detoxification), DNA repair, and apoptotic regulation. Excessive...
Kentucky--History--1792-1865; Southwest, Old--History; Mississippi River Valley--History
This paper is involved in a study of the intrigues of Kentuckians for the securing of the Mississippi River as a free waterway for the marketing of their produce and the consequent improvement of the condition of Kentuckians in every way. The...
Business logistics; Production management; Manufacturing processes; Industrial efficiency
In today's competitive business environment, companies face enormous pressure and must continuously search for ways to design new products, manufacture and distribute them in an efficient and effective fashion. After years of focusing on reduction...
Electronic commerce--Corrupt practices--Prevention; Internet advertising--Corrupt practices; Internet fraud
Online search advertising is currently the greatest source of revenue for many Internet giants such as Google™, Yahoo!™, and Bing™. The increased number of specialized websites and modern profiling techniques have all contributed to an...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 18. No. 29. but is actually Vol. 18. No. 30.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. An article has been clipped from the top corner of pages one and two of this issue.
African American journalists; African American politicians; African American newspapers; African Americans; Politics & government; Politicians; Race relations; Democratic Party (Ky.); Mammoth Life and Accident Insurance Co. (Louisville, Ky.);...
Interview with William J. Ealy, Louisville newspaperman and political activist. This interview was conducted on August 5 and 22, 1977 by Dwayne Cox of the University of Louisville Oral History Center. Mr. Ealy discusses his early life and education...
Photography--Psychological aspects; Mourning customs in art; Mourning customs in literature; Phenomenology and art
The creation of liminal spaces has been used for centuries cross-culturally to create sacred or taboo meanings in rituals, people, places, or objects. Liminality is constructed by the overlapping of cultural categories and "ruptures" an...
St. Irene (Church : Istanbul, Turkey); Irene, Empress of the East, 752?-803; Constantine V Copronymus, Emperor of the East, 718-775; Apses (Architecture)--Turkey--Istanbul; Art patronage--Turkey--Istanbul--History--8th century
The mosaic of the cross in the apse of Hagia Eirene in Constantinople is examined in order to determine the imperial patron responsible for it's construction. Key points in this study are Orthodox image veneration, Iconoclast doctrine and the...
A projected high penetration of battery electric vehicles (BEV s) in the market will introduce an additional load in the electricity grid. Furthermore, uncontrolled BEV charging from residential users will exacerbate the existing peak load during...
Transportation--Kentucky--History; Kentucky. Board of Internal Improvement--History
For a brief period of fifteen years, the Board of Internal Improvement occupied a place of prominence in the political and economic affairs of Kentucky. From its
creation in 1835, until the revision of the constitution in 1850, the board spent vast...
Aims. The primary aim of this randomized, controlled, blinded clinical trial was to compare the clinical and histologic results of ridge augmentation comparing a cancellous block allograft to a particulate mineralized freeze dried bone allograft...
Marconi, Guglielmo, marchese, 1874-1937; Radio broadcasting--Social aspects
This dissertation is a rhetorical analysis of Guglielmo Marconi's wireless. Texts surrounding the invention reveal intersections between technology and society and communicate information about the wireless through tropes of progress. The wireless...
Fantasy fiction, American; Fantasy fiction, Japanese
This creative thesis follows the opening story arc to a larger fiction project in the genre of high fantasy fiction. Structurally and stylistically, by incorporating contemporary contributions to the genre from Japanese popular culture, this story...
After a careful study of Madison Cawein's poetry, and comparing his views on religion and philosophy with those of some of the great English poets, Wordsworth, Shelley, Byron, Tennyson and Browning, I shall summarize them as follows, and treat each...