The discovery of carbon nanotubes and subsequently graphene has led to an interest in carbon materials as sensing elements due to their unique properties. Graphene is a 2-dimensional material that has a large surface area that can be exposed to...
Pancreatic beta cells are extremely vulnerable to the destruction of Reactive Oxygen Species (ROS). In both type 1 and type 2 diabetes ROS are involved in the loss of U+000DF-cells. We hypothesized that the deficiency in ROS detoxifying system of...
Lung cancer is the deadliest type of known cancer in the United States, claiming hundreds of thousands of lives each year. However, despite the high mortality rate, the 5-year survival rate after resection of Stage 1A non–small cell lung cancer...
Recently our lab has shown that with broadband stimuli (either visual noise or natural scenes), performance for detecting oriented content is worst at horizontal, best at the obliques, and intermediate at vertical orientations--an anisotropy...
The role of the active site tyrosine residue in the Co-C5' bond activation in the
context of adenosylcobalamin-dependent mutases has been computationally
investigated. The density functional, complete active space self-consistent field
and quantum...
Persecution--England--History--16th century; Martyrdom--Christianity--England; Great Britain--History--Elizabeth, 1558-1603; Great Britain--History--Mary, 1553-1558
This thesis is a historical examination of the Marian and Elizabethan persecutions. Through the analysis of primary sources dating from the persecutions, the process of persecution in Reformation England is examined. This thesis uncovers the...
In this work, micro fabrication techniques are explored not only to simplify the production of complex lab on-a-chip devices (LOC), but also micro fabrication will be utilized to create intelligent design features that will enhance an...
Crossover design is a type of longitudinal study with each subject receiving different treatments in different time periods. It has been used frequently in the pharmaceutical industry and other medical fields to investigate the safety and efficacy...
Oxygen is critical to aerobic metabolism, but hyperoxia is cytostatic and cytocidal. The precise mechanisms involved in hyperoxic cell injury remain incompletely understood although there is substantial support for the possibility that hyperoxia...
Vertical axis wind turbines (VAWTs) are devices to convert wind energy into electricity. Unlike horizontal axis wind turbines (HAWT) where the main rotor shaft is set horizontally, VAWTs use vertical rotor shaft. Unlike HAWTs, VAWTs can be...
N-acetyltransferase 1 (NAT1) is a phase II metabolic enzyme responsible for the biotransformation of aromatic and heterocyclic amine carcinogens such as 4-aminobiphenyl (ASP). NAT1 catalyzes N-acetylation of arylamines as well as the 0-acetylation...
Executions and executioners--Press coverage; Mass media and public opinion; Capital punishment in popular culture; Death row inmates--Press coverage
The public's exposure to state sanctioned killings is limited to the mass media representations such as editorials, news reports, feature films, and books. Therefore it is important to examine the process of execution and its relation to the media...
This thesis deals with the events and issues which were connected with the 1935 gubernatorial election. There is first a brief sketch of Kentucky politics prior to the 1935 election. Particular interest is given to the history of the Democratic...
Remote terminal units (RTUs) are perimeter supervisory control and data acquisition (SCADA) devices that measure and control actual physical devices. Cyber security was largely ignored in SCADA for many years, and the cyber security issues that now...
Indians of North America--Kentucky--Bullitt County--Antiquities; Excavations (Archaeology)--Kentucky--Ashworth Rockshelter site; Ashworth Rockshelter site (Ky.)
Reinvestigation of a National Register property, the Ashworth Rockshelter (15BU236), northeast of Shepardsville, Bullitt Co., Kentucky, revealed stratified Early Archaic through Mississippian components (ca. 7900 B.C.-1500 A.D.). Primary occupation...
Few previous studies have compared microbial communities in subterranean and surface environments. Chemical analyses used to characterize the surface and cave microbial environments indicated limited exchange between surface and subsurface waters....
This dissertation is an exploratory study of the indicators of receptivity that communities portray towards international service-learning programs. Historically, programs such as service learning programs choose communities and other working...
Exocytosis of intracellular granules is critical for conversion of inactive, circulating neutrophils to fully activated cells. The p38 MAPK pathway plays a central role in neutrophil exocytosis, although its mechanism of action is unknown. We used...
English ballads and songs--Religious aspects; Scottish ballads and songs--Religious aspects; Religion in literature
The present study of the religious element in the popular ballads is based largely on Mr. George L. Kittredge's edition of Mr. Francis J. Child's collection of English and Scottish popular ballads, the completeness of which, up to this time, has...
The current status of our knowledge of synaptic plasticity comes largely from studies of the hippocampus and the context of learning and memory. We remain largely ignorant of plasticity in other neural systems and contexts. The molecular basis of...
