Soon after the atomic theory was established, it was found that the plant uses as sources of food not only the air and water, but also different constituents of the soil, dissolved in the soil moisture—the mineral nutrients. Ashes of different...
In today's world of private information and mass communication, there is an ever increasing need for new methods of maintaining and protecting privacy and integrity of information. This thesis attempts to combine the chaotic world of cellular...
Down syndrome--Patients; Williams syndrome--Patients; Social interaction in children; Social perception in children
The present project examined the regulatory function of social referencing in two neurodevelopmental disorders that have been well defined genetically and are characterized by differing patterns of socio-cognitive development: Down syndrome (DS)...
The objective of this thesis is to develop computer programs for the dynamic analysis of structures. For a shear building two computer programs were developed: (1) Dynamic Analysis of a Shear Building within the Elastic Range and (2) the Dynamic...
Standard regularity assumptions for regression models are not satisfied in segmented regression models with an unknown change point, and consequently standard asymptotic results and inferential methods for confidence estimation are not applicable....
The advent of larger storage spaces, affordable digital capturing devices, and an ever growing online community dedicated to sharing images has created a great need for efficient analysis methods. In fact, analyzing images for the purpose of...
The lipid aldehydes, 4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are reactive α,β-unsaturated aldehydes generated during the peroxidation of lipids and are implicated in the pathogenesis of several oxidative-stress mediated diseases,...
c-Myc dysregulation is one of the most common abnormalities found in human cancer. MicroRNAs (miRNAs) are functionally intertwined with the c-Myc network as multiple miRNAs are regulated by c-Myc, while others directly suppress c-Myc expression. In...
For more than a hundred million years, male plethodontid salamanders have
utilized non-volatile, proteinaceous courtship pheromones to regulate female mating
receptivity and promote mating success. These pheromones - which are delivered...
N-acetyltransferase 1 (NAT1) is a phase II metabolic enzyme responsible for the biotransformation of aromatic and heterocyclic amine carcinogens such as 4-aminobiphenyl (ASP). NAT1 catalyzes N-acetylation of arylamines as well as the 0-acetylation...
The purpose of this project was to compare the accuracy and reliability of linear measurements made on 2D projections and 3D reconstructions using Dolphin 3D software (Chatsworth, CA) as compared to direct measurements made on human skulls. The...
The chaperone heat shock protein 90 (Hsp90) regulates physiologically and
pathological cellular processes, by binding and stabilizing kinases involved in basal
cellular functions and in cellular responses to stress, respectively. I hypothesize...
Hypoxia is characterized by an inadequate oxygen supply to the tissues in
proportion to their metabolic needs, and is a primary factor in traumatic CNS
injury, strokes, cardiopulmonary diseases, and obstructive sleep apnea. The
cAMP-dependent...
Mary, Blessed Virgin, Saint--Art; Breastfeeding in art
This dissertation is an analysis of Italian late medieval and Renaissance peoples’ response to the Madonna lactans image. Although the images that comprise this type are similar in that Mary holds Christ at her breast, they vary widely in...
Herbig Ae stars are young stars usually surrounded by gas and dust in the form of a disk and are thought to evolve into planetary systems similar to our own. We present a multi-wavelength examination of the disk and environment of the Herbig Ae...
Blind--Education--Arithmetic; Arithmetic--Study and teaching--Data processing; Speech synthesis
The design and development of a microprocessor-controlled mathematics trainer is described. The trainer is designed primarily for a blind student, and uses synthetic speech to verbally present mathematics problems in the form of incomplete...
This thesis is divided into two parts below. Part I Adriamycin (ADR) can produce nephrotoxicity in rodents. The underlying mechanism may relate to ADR induced oxidative stress. In this study, we used transgenic mice (NMT3), which over-expressed the...
This project investigated the effect of hypothermia on the monocyte response with the goal of understanding, which intracellular processes are affected by hypothermia leading to differences in cytokine secretion. A better understanding of the...
Bcl-2 proteins are major regulators of cellular responses to various apoptotic stimuli. Among them, overexpression of the anti-apoptotic BcI-2 protein BcI-xL modulates organelle-specific apoptotic pathways. To understand the mechanisms by which...
Ischemic heart disease is the leading cause of mortality and morbidity in Western societies. Thus, understanding the molecular mechanisms to reduce myocardial ischemia and limit infarction size are of great importance. Ample evidence has shown that...
