The role of the active site tyrosine residue in the Co-C5' bond activation in the
context of adenosylcobalamin-dependent mutases has been computationally
investigated. The density functional, complete active space self-consistent field
and quantum...
Vehicles--Environmental aspects; Traffic flow--Environmental aspects; Motor vehicles--Motors--Exhaust gas
The purpose of this dissertation is to develop a methodology to estimate the temporal Environmental Traffic Capacity (ETC) for urban streets. The approach constitutes the main procedure of ETC calculation and an experimental process of developing...
The ability of L. pneumophila to cause disease depends on its replication in alveolar macrophages. Infectivity and the expression of various virulence traits is triggered at post exponential growth phase. We show that unlike quiescent macrophages,...
General. – The Characaeae is the only extant family of an ancient and unique group of nonvascular aquatic plants which are classified as a separate division, the Charophyta (Groves and Bullock-Webster, 1920; Zaneveld, 1940; Imahori, 1954; Bold,...
Ozone forecast models using nonlinear regression (NLR) have been successfully applied to daily ozone forecast for seven metro areas in Kentucky, including Ashland, Bowling Green, Covington, Lexington, Louisville, Owensboro, and Paducah. In this...
Intelligent transportation systems; Air quality; Air--Pollution
Environmental or air quality impacts of Intelligent Transportation Systems (ITS)
are very difficult to measure. Some researchers have attempted to quantify the effects of
individual ITS application on emissions; yet, the effects of ITS as a whole...
This thesis is written to investigate if and how far the German credit financial market could be promising for consulting fees in the field of mortgage loan banking. The problem identified is an extensively discussed issue in the German credit...
This dissertation deals with various imidazole compounds with emphasis on hydrogen bond interactions and weaker intermolecular forces. New amide functionalized polyimidazole metal binding pockets are able to form intramolecular six-membered...
The purpose of this research project is to evaluate the feasibility of interhospital patient transfers (within a hospital corporation referred to as NESW Hospital Co.) as a means of reducing emergency department overcrowding. Customer satisfaction...
Whitestone, Henry, 1819-1893; Architects--United States
Henry Whitestone (1819-1893) practiced architecture in the
nineteenth century when the prevailing mode in architectural styles
was a series of historical revivals. His work, with few exceptions,
was entirely within the style of the Italian...
Females have a higher incidence of autoimmune diseases than males for reasons that are currently unknown. CD4+CD25+ regulatory T cells play an important role in the maintenance of immunological homeostasis and self-tolerance by suppressing...
Medical education; Medical students; Hospital College of Medicine, Louisville (Ky.)
Catalog for Hospital College of Medicine 1884. Includes medical faculty, program information, enrolled students for 1883, and graduates for 1874-1883. Printed on cover: Announcement of the Regular Session of 1884 of the Hospital College of...
Nitrile hydratase (NHase) is a metalloenzyme that contains a non-heme iron (III)
or non-corin cobalt (III) in a non-redox active role. NHase is used as biocatalyst in the
industry for the hydrolysis of nitriles to arnides. The trivalent metal ions...
20S proteasome, essential component of protein degradation mechanism, is important to maintain homeostasis. Its malfunctions have been associated with several pathological conditions. This study presents an extensive study of murine cardiac 20S...
Multiple normalization methods have been proposed for the analysis of microRNA microarray expression profiles but there is no consensus method. One of the more robust methods, quantile normalization, is commonly used in transcript (mRNA) studies...
4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are highly reactive á,â-unsaturated aldehydes. 4-HNE and acrolein are generated in vivo as products of lipid peroxidation. These aldehydes are implicated in the onset of several diseases...
The purpose of this project was to compare the accuracy and reliability of linear measurements made on 2D projections and 3D reconstructions using Dolphin 3D software (Chatsworth, CA) as compared to direct measurements made on human skulls. The...
Medical education; Medical students; Hospital College of Medicine, Louisville (Ky.)
Catalog for Hospital College of Medicine 1885. Includes faculty, program information, enrolled students for 1884, and graduates 1874-1884. Printed on cover: Announcement of the Regular Session of 1885 of the Hospital College of Medicine, Medical...
A common research interest in medical, biological, and engineering research is determining whether certain independent variables are correlated with the survival or failure times. Standard statistical techniques cannot usually be applied for...