Metastasis is a complex process requiring directed migration of metastatic cells to favorable microenvironments. Increased CXCR4 expression has been implicated in more invasive, aggressive and metastatic tumor phenotypes and poor patient survival...
The vaccinia virus complement control protein (VCP) is involved in the modulation of the host inflammatory response during vaccinia virus infection. It possesses the ability to inhibit both classical and alternative pathways of complement...
Interactions between chemokines and their receptors are involved in organ- specific homing and propagation of metastatic breast cancer (BrCa) cells. BrCa cells express higher levels of CXCR4 and CXCR7 mRNA and cell surface protein, than normal...
Chronic periodontitis is strongly associated with composition of the oral biofilm
occupying the gingival crevicular aspect of the tooth and its associated root. Some gram-negative,
"red complex" bacteria instigate periodontal bone loss in...
Herbig Ae stars are young stars usually surrounded by gas and dust in the form of a disk and are thought to evolve into planetary systems similar to our own. We present a multi-wavelength examination of the disk and environment of the Herbig Ae...
Inflammation is now recognized as an important factor in several age-related diseases such as arthritis, atherosclerosis, multiple sclerosis and diabetes. In each case, sub-clinical chronic inflammation occurs over years and leads to progressive...
Periodontitis--Age factors; Natural immunity; Age factors in disease
Periodontal disease arises from excessive host inflammatory responses to the tooth-associated microbial biofilm, known as dental plaque. Severity ranges from superficial inflammation of the gingivae (gingivitis) to extensive destruction of...
Acrolein--Toxicology; Stem cells--Effect of pollution on
Acrolein is a common pollutant present in ambient air, automobile exhaust, and tobacco smoke. Previous studies show that exposure to acrolein increases cardiovascular disease risk. To determine whether acrolein affect cardiovascular regeneration,...
4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are highly reactive á,â-unsaturated aldehydes. 4-HNE and acrolein are generated in vivo as products of lipid peroxidation. These aldehydes are implicated in the onset of several diseases...
Pituitary tumor transforming gene ( PTTG ), also known as securing, is a novel oncogene that is expressed at high levels in most of the tumors analyzed to date. Overexpression of PTTG in mouse fibroblast(NIH 3T3) cells increases cell proliferation,...
Previous studies on the mechanistic induction of anti-tumor responses by IL-12 cytokine therapy have focused on the adaptive immune response, specifically the activation NK cells and T cells as the primary targets of IL-12 treatment. In contrast,...
Law and legislation--Kentucky; Law and legislation--Virginia
Littell's Statute Law of Kentucky, published from 1809-1819, has the first critically edited compilation of Kentucky statutes. It has long been recognized by lawyers as one of the founding documents of state law and by historians of early Kentucky...
Law and legislation--Kentucky; Wills--Kentucky; Justice of the peace--Kentucky; Sheriffs--Kentucky
Littell's Statute Law of Kentucky, published from 1809-1819, has the first critically edited compilation of Kentucky statutes. It has long been recognized by lawyers as one of the founding documents of state law and by historians of early Kentucky...
Law and legislation--Kentucky; Law and legislation--Virginia
Littell's Statute Law of Kentucky, published from 1809-1819, has the first critically edited compilation of Kentucky statutes. It has long been recognized by lawyers as one of the founding documents of state law and by historians of early Kentucky...
Law and legislation--Kentucky; Law and legislation--Virginia; Constitutions--Kentucky; Constitutions--Virginia
Littell's Statute Law of Kentucky, published from 1809-1819, has the first critically edited compilation of Kentucky statutes. It has long been recognized by lawyers as one of the founding documents of state law and by historians of early Kentucky...
Law and legislation--Kentucky; Law and legislation--Virginia; Constitutions--Kentucky; Constitutions--Virginia
Littell's Statute Law of Kentucky, published from 1809-1819, has the first critically edited compilation of Kentucky statutes. It has long been recognized by lawyers as one of the founding documents of state law and by historians of early Kentucky...
Law and legislation--Kentucky; Law and legislation--Virginia
Littell's Statute Law of Kentucky, published from 1809-1819, has the first critically edited compilation of Kentucky statutes. It has long been recognized by lawyers as one of the founding documents of state law and by historians of early Kentucky...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a tear down the center of each page of this issue.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 32. No. 26. but is actually Vol. 32. No. 30. There is a tear across the center of each page that...
