Monoclonal antibodies directed toward tumor associated antigens are FDA approved anticancer reagents used commonly in the clinic. Administered antibodies initiate tumor cell death through several mechanisms. Improving immune mediated mechanisms,...
In a nonlocally compact Polish abelian group G, we will consider two notions of smallness of subsets of G. Those subsets of G which are topologically small are said to be meager, and those which are measure-theoretically small are Haar null. We...
Regression analysis is a statistical method used to relate a variable of interest, typically y (the dependent variable), to a set of independent variables, usually, X1, X2,...,Xn . The goal is to build a model that assists statisticians in...
The process of designing the settings and lighting for a show is an adventure; it's a story that has the normal components of any good story, a beginning, middle and end. There is tension, conflict, climax and resolution. It contains characters who...
Fiber-reinforced polymer matrix composites (PMCs) using high-temperature thermoplastics as the matrix material represent a lightweight design solution for applications above 250°F. This is often required for aircraft structures subjected to...
Vicinal dithioethers and alkenyl thioethers were synthesized under environmentally
friendly conditions using alkyne and thiol in water. Alkynes were also used to develop a
multibond-fonning reaction that fonned cyclic ketones or ketoesters through...
Nuclear Factor of Activated T-cells (NFAT) is a calcium-responsive transcription factor that orchestrates immune response and cardiovascular development. NFAT is also present in neurons and glia from the Central Nervous System (CNS) where it...
T cells; Disease susceptibility; Lupus; Sex factors in disease
Females are more susceptible to autoimmune disease than males. In several mouse models of disease, castration of males exacerbates disease while androgen treatment ameliorates disease. These data suggest hormones can have an influence on disease...
Monophosphoryl Lipid A (MPLA), a derivative of LPS endotoxin, is a TLR4 agonist that displays as little as 0.1-1% as much toxicity as its parent molecule while retaining immunostimulatory properties. We discovered that MPLA activates a TRIF-biased...
Nanoparticles; Imaging systems in medicine; Imaging systems in biology
Gold nanoparticles (GNPs) have shown beneficial properties for biomedical use, e.g., their non-toxic nature and surface properties for easy modification. Upon receiving light, they generate a strong surface plasmon field, which can alter the...
In submitting this thesis, the writer does not pretend to have made even an approximation of exhaustive study of the Hecyra: this thesis is merely a study of the play from certain viewpoints which also make no claim to completeness. No originality...
In the bulk of experiments on animal feeding the Albino Rat has served as the experimental animal. It has been proved that any diet which brings about satisfactory growth in white rats will also cause a young child to grow satisfactorily....
Law and legislation--Kentucky; Law and legislation--Virginia; Constitutions--Kentucky; Constitutions--Virginia
Littell's Statute Law of Kentucky, published from 1809-1819, has the first critically edited compilation of Kentucky statutes. It has long been recognized by lawyers as one of the founding documents of state law and by historians of early Kentucky...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol 3. No. 26. but is actually No. 27. Portion missing from the middle of the front page.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a tear down the center of each page of this issue.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a tear down the center of each page of this issue and portions of each page are very faded.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. An article has been clipped from the center of pages one and two of this issue.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 28. No. 50. but is actually Vol. 28. No. 52. This issue is four pages.
