Parkinson's disease--Treatment; Stem cells--Therapeutic use
Parkinson's disease (PD) is a hypokinetic movement disorder resulting from the
progressive neurodegeneration of the dopaminergic nigrostriatal system in the brain and
the resulting imbalance between dopamine and acetylcholine in the basal ganglia...
Protein C (PC) is an important anticoagulant, antithrombotic, and antiinflammatory in blood plasma. PC deficiency can lead to severe venous thrombotic events, including lung embolism, stroke, and heart attack. In the body, PC is activated only when...
The purpose of this study was to determine the effects of acute glutamine supplementation on maximal performance and recovery from high-intensity exercise. In a placebo-controlled, crossover study, seven (six males and one female) healthy subjects...
Freshwater zooplankton; Global warming; Nitrogen--Environmental aspects
Aquatic ecosystems face major transformations as humans increasingly alter their environment by introducing exotic species and changing the temperature regime and nutrient availability of freshwater systems. The impacts of such alterations of...
Freer, Charles Lang, 1856-1919; Freer Gallery of Art
This qualifying paper examines the contradiction of a public museum dedicated to one man's vision of art collecting. Charles Lang Freer established the Freer Gallery of Art in 1906, regarded as the first national public art museum on the National...
Medical education; Medical students; Hospital College of Medicine, Louisville (Ky.)
Catalog for Hospital College of Medicine 1888. Includes faculty, program information, enrolled students 1887, graduates 1884-1887, and university information. Printed on cover: Announcement of the Regular Session of 1888 of the Hospital College of...
Self-control in children; Crime and race; Parent and teenager; Teenagers--Family relationships
This study seeks to examine whether racial disparities in offending can be explained through self-control theory. The study utilized longitudinal responses of a nationally representative sample of 1700 adolescents. Parenting and self-control...
African American men--Social conditions; Crime and race; Peer pressure
The initial goals of this study include locating and identifying the taxonomic groups mentioned in Moffitt's (1993) (i.e. life-course persistent offenders, adolescent-limited offenders) using data from the National Longitudinal Survey 1997...
Periodontitis; Iron--Health aspects; Iron in the body
The dental pathogen A. actinomycetemcomitans, a Gram- negative organism, has been associated with aggressive forms of periodontitis. A. actinomycetemcomitans requires iron to grow. In the host, iron-binding proteins such as transferrin,...
It has been shown that GSK3 β plays a critical role in the inflammation response by differentially regulating MyD88-dependent pro- and anti-inflammatory cytokines production in TLR4-stimulated innate immune cells. The work included in this...
Alcoholic liver disease (ALD) ranks among the major causes of morbidity and mortality in the world and effects millions of patients each year. Progression of ALD is well characterized and is actually a spectrum of liver diseases, which progresses...
For persons with disabilities, access to transportation is necessary for integration into society. The Americans with Disabilities Act (ADA) has been instrumental in assuring transportation access to individuals with disabilities for purposes of...
Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) catalyze the detoxification and/or activation of aromatic and heterocyclic amine carcinogens by two pathways. This metabolism reaction can lead to the detoxification by Nacetylation, or...
This dissertation explores the physical and biological factors that control zooplankton population growth rates in the Ohio River (USA). I employed both observational studies and a mesocosm experiment to ascertain zooplankton population and...
Human adenoviruses (Ads) can infect and replicate in cells at different cell-cycle stages. Ads with the E1 B55K deletion preferentially replicate in cancer cells and cause oncolysis. Our laboratory has previously shown that the Ad E1 b gene is...
This study investigates the placebo effect in randomized controlled trials of low back pain. This effect has not been analyzed over time or in respect to low back pain. A meta-analysis was performed using the Pubmed/Medline database for low back...
Simmons University (Louisville, Ky.); African American universities and colleges; African Americans--Education (Higher); Education
Includes names of faculty and students, information about the university and its courses, and photos of campus buildings and faculty. The university has gone by many names since its founding in 1879: The Kentucky Normal and Theological Institute...
Medical education; Medical students; Hospital College of Medicine, Louisville (Ky.)
Catalog for Hospital College of Medicine 1890. Includes faculty, program information, enrolled students 1889, graduates 1874-1889, and university information. Printed on cover: 1890. The Central University of Kentucky. Medical Department. Hospital...
Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease with poor prognosis.
To address this disease broadly, the candidate engaged in clinical work, literature
analysis, database analysis, and laboratory work. The clinical work culminated...
CDCIWHO only "recommends" that rings be removed under gloves because of cross-contamination between health care workers and patients. Microbiological samples of oral streptococci beneath rings and between fingers under non-sterile exam...
