Guanine-rich oligonucleotides (GROs) are being developed as a novel anticancer agents. GROs exhibit potent antiproliferative properties against several malignant cell lines and in established in vivo tumor models. In a recent Phase I clinical trial...
Yevgeny Yevtushenko wrote five poems that critiqued Soviet society. The poems, on topics as diverse as anti-Semitism, the suppression of humor, the mistreatment of women, state repression, and bureaucracy, were written at separate times and for...
The process of designing the settings and lighting for a show is an adventure; it's a story that has the normal components of any good story, a beginning, middle and end. There is tension, conflict, climax and resolution. It contains characters who...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 16. No. 44. but is actually Vol. 16. No. 45.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There are significant tears and portions missing along the sides of pages seven and eight of this issue.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. Pages six and seven of this issue are very faded.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. Page seven of this issue is very faded.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 17. No. 33. but is actually Vol. 17. No. 38. This issue is twelve pages. There are illegible...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 3. No. 32. but is actually No. 33.
Sierra Leone--History--Civil War, 1991-2002--Causes; Sierra Leone--Social conditions; Postwar reconstruction--Sierra Leone
This multilayered study is an appraisal of some of the ongoing post-conflict reconstruction efforts in Sierra Leone in light of the causes of the conflict, which lasted from 1991-2002. It begins by providing a critical examination of the historical...
The application of carbon nanotubes (CNTs) has captivated the curiosity of today's experts due to the escalating potential in the field of electronic detection of biomolecules. Their extreme environmental sensitivity and small size make them ideal...
Genes in folate metabolizing pathway are responsible for modulating key enzymes in folate metabolisms necessary for DNA synthesis and repair and influence DNA methylation. Irregularity in DNA methylation may modify tumor phenotype response to...
It has been estimated that 30% of all cancer deaths in the U.S. are associated with obesity. It is well-established that obesity promotes low-grade chronic inflammation, however the mechanisms by which obesity-induced chronic inflammation may...
Vicinal dithioethers and alkenyl thioethers were synthesized under environmentally
friendly conditions using alkyne and thiol in water. Alkynes were also used to develop a
multibond-fonning reaction that fonned cyclic ketones or ketoesters through...
Thirty smokers were solicited from the Wichita, Kansas community via the newspaper and broadcast media for a stop-smoking project. The volunteers were assigned to one of two treatments: double smoking or a modification of Von Dedenroth's (1964)...
Urbanization disrupts natural soil profiles and as watersheds are
urbanized, their surfaces become impervious and this will result in
reduction of infiltration. For this reason, many cities are facing problems
with treating runoff water. Best...
Very little is known about the acridine ring system. Such compounds as acriflavine, brucine and strychnine are generally believed to contain the acridine ring system. These compounds are all very important drugs. Acriflavine has been used in the...
Soon after the atomic theory was established, it was found that the plant uses as sources of food not only the air and water, but also different constituents of the soil, dissolved in the soil moisture—the mineral nutrients. Ashes of different...
In the course of their life cycle, mosquitoes undergo an ontogenetic niche shift; immature larval development occurs within an aquatic habitat from which adult mosquitoes subsequently disperse into the terrestrial environment. While adult female...
The purpose of this study was to determine the effects of acute glutamine supplementation on maximal performance and recovery from high-intensity exercise. In a placebo-controlled, crossover study, seven (six males and one female) healthy subjects...