Interactions between chemokines and their receptors are involved in organ- specific homing and propagation of metastatic breast cancer (BrCa) cells. BrCa cells express higher levels of CXCR4 and CXCR7 mRNA and cell surface protein, than normal...
This dissertation deals with various imidazole compounds with emphasis on hydrogen bond interactions and weaker intermolecular forces. New amide functionalized polyimidazole metal binding pockets are able to form intramolecular six-membered...
Heart--Diseases--Diagnosis; Diagnostic imaging; Magnetic resonance imaging; Imaging systems in medicine
Many cardiac diseases, such as myocardial ischemia, secondary to coronary artery disease, may be identified and localized through the analysis of cardiac deformations. Early efforts for quantifying ventricular wall motion used surgical implantation...
Parking garages--Automation; Parking garages--Design and construction
Automated vehicle storage/retrieval system (AVS/RS) technology is relatively new. It has been applied successfully in several European facilities in 1990s. AVS/RS is a flexible system that is a viable alternative to automated storage/retrieval...
Background The anthracycline doxorubicin (DOX) is widely used as an effective antineoplastic drug. Cardiotoxicity leading to congestive heart failure is the primary factor limiting the clinical use of DOX. However, although a variety of approaches...
Business logistics; Production management; Manufacturing processes; Industrial efficiency
In today's competitive business environment, companies face enormous pressure and must continuously search for ways to design new products, manufacture and distribute them in an efficient and effective fashion. After years of focusing on reduction...
In the year 1573 when Shakespeare and Marlowe were already boys of nine, Chapman in adolescence, Spenser, Lyly and Richard Hooker men of twenty, John Donne, then important to only a few but destined to the company of royalty, was born. Walton...
We have measured the temperature-dependent thermal conductivity, K(T) of single walled carbon nanotubes from 300 K to 8 K by 3w methods. K(T) exhibits linear temperature dependence in the entire temperature range. Our results are in good agreement...
Medical education; Medical students; Louisville Medical College
Catalog for Louisville Medical College 1893-1894. Includes faculty, program information, and graduates 1893. Printed on cover: Annual Announcement Louisville Medical College Louisville, KY.
Through differential display PCR, Munc13-3 was identified as a gene whose relative expression in the visual cortex corresponds to critical period plasticity. Expression of the gene was low at the peak of the critical period and expression was high...
In the retina, the receptive fields (RFs) of most neurons are comprised of an excitatory center and a suppressive surround. Retinal ganglion cell (RGC) RF center excitatory input arises from bipolar cell (BC) inputs, while their surround arises...
Night vision--Genetic aspects; Vision disorders--Genetic aspects
Mutations in the NYX gene, encoding the novel protein nyctalopin, cause human congenital stationary night blindness type 1 (CSNB1). CSNB1 is an X-linked recessive condition and is identified by a loss of the electroretinogram (ERG) b-wave while the...
Cadman, S. Parkes (Samuel Parkes), 1864-1936; Radio in religion--United States--History; Religious broadcasting--Christianity--History; Religious broadcasting--United States--History; Christianity--United States--20th century
S. Parkes Cadman (1864-1936), a Christian minister at Central Congregational Church in Brooklyn, New York from 1901 to 1936, was a popular religious figure in interwar America. From 1924 to 1928, Cadman served as president of the Federal Council of...
Self-knowledge in literature; Feminism in literature; Mind and body in literature
That Terrifying Center is a creative and philosophical experiment in the transmission of corporeal experiences and socio-cultural knowledge through poetry. I am bringing together the seemingly disparate threads of my studies into one...
c-Myc dysregulation is one of the most common abnormalities found in human cancer. MicroRNAs (miRNAs) are functionally intertwined with the c-Myc network as multiple miRNAs are regulated by c-Myc, while others directly suppress c-Myc expression. In...
Star Wars films--History and criticism; Myth in motion pictures; Lucas, George, 1944-
The Star Wars franchise is one of the most successful film series of all time. The original three
movies, along with the more recent three prequels, serve as the foundation to a vast empire of
Star Wars television shows, action figures, comic...
Metastasis is a complex process requiring directed migration of metastatic cells to favorable microenvironments. Increased CXCR4 expression has been implicated in more invasive, aggressive and metastatic tumor phenotypes and poor patient survival...
Cilicia--History--Armenian Kingdom, 1080-1375; Mongols--History--To 1500; Mamelukes--History--To 1500; Christianity and other religions--Islam; Islam--Relations--Christianity
This work seeks to fill a gap in the academic literature concerning the study of the Ilkhanid Mongols of the Middle East during the thirteenth and fourteenth centuries CE using Armenian, Persian, Arabic, and Syriac primary sources in English...
