Parkinson's disease--Treatment; Stem cells--Therapeutic use
Parkinson's disease (PD) is a hypokinetic movement disorder resulting from the
progressive neurodegeneration of the dopaminergic nigrostriatal system in the brain and
the resulting imbalance between dopamine and acetylcholine in the basal ganglia...
Industrial relations--United States; Industries--Social aspects--United States
The original intention of this dissertation was to have been a brief treatment of some phases of our modern industrial problem. Later, however, it was decided to offer suggestions for solutions to these various problems. This I have attempted to do...
Supervisory control systems--Security measures; Automatic data collection systems--Security measures
This thesis describes the development of a prototype security hardened field device (such as a remote terminal unit) based on commodity hardware and implementing a previously developed security architecture. This security architecture has not been...
This thesis is an economic and historical examination of Keeneland racetrack in Lexington, Kentucky. The material commences with a historical overview of the role of sport and recreational activities in the United States. Putting sport and leisure...
Gary Snyder's poetry conveys Zen states of consciousness through unconventional grammar and syntax. From his first book Riprap in 1959 to his last collection of poems, Mountains and Rivers Without End in 1996, he has confronted the challenge of...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue is twelve pages and is made up of the normal eight pages with an additional four page section called The...
Graft rejection; Diagnostic imaging; Postoperative care
The fourth hand transplant recipient in Louisville lost his graft at nine months post transplant from ischemia due to severe graft arteriopathy. Conventional imaging techniques and clinical measurements, including CT angiography and measurements of...
Alcoholic liver disease (ALD) is a serious concern for the world's population. It is one of the leading causes of death and is also a huge economic burden. The biochemical mechanisms responsible for ALD are incompletely understood, therefore there...
DENIOS manufactures steel structures for the storage, handling and containment of chemicals. The company has recently relocated into a larger manufacturing facility. This move will allow the manufacturing capacity of the company to grow for the...
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease with poor prognosis.
To address this disease broadly, the candidate engaged in clinical work, literature
analysis, database analysis, and laboratory work. The clinical work culminated...
Chronic periodontitis is strongly associated with composition of the oral biofilm
occupying the gingival crevicular aspect of the tooth and its associated root. Some gram-negative,
"red complex" bacteria instigate periodontal bone loss in...
Background. Progression of alcoholic liver disease (ALD) is associated with an increase in fibrin extracellular matrix (ECM) and inflammation. Previous studies have shown that this accumulation of fibrin in ALD is mediated by impaired fibrinolysis....
Spinal cord injury (SCI) can be divided into two distinct stages, an initial mechanical impact and a later "secondary injury" resulting from a cascade of cytokines triggering a spreading demyelination and apoptosis of neurons and glia...
While the character of women in the plays of ancient times has ever played an important part in the history of the drama, the appearance of women in the feminine roles is a distinctly recent development. It might well be said that this is a fairly...
Fantasy fiction, American; Fantasy fiction, Japanese
This creative thesis follows the opening story arc to a larger fiction project in the genre of high fantasy fiction. Structurally and stylistically, by incorporating contemporary contributions to the genre from Japanese popular culture, this story...
Musical pitch--Data processing; Sound--Recording and reproducing--Digital techniques
Many mathematical formulas and algorithms exist to identify pitches formed by human voices, and this has continued to be popular in the fields of music and signal pro-cessing. Other systems and research perform real time pitch identification...
Alcohol; Distillation; Alcoholic beverages; Corn--Utilization; Whiskey industry
In the whisky industry there is a balance between the desire to adhere to the traditional production process and the desire to increase profit margins. One solution that follows both stipulations is to increase the alcohol yield of a given batch of...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 10. but is actually Vol. 11. Page seven of this issue is very faded.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue is twelve pages and is made up of the normal eight pages with an additional four page section called The...
