Night vision--Genetic aspects; Vision disorders--Genetic aspects
Mutations in the NYX gene, encoding the novel protein nyctalopin, cause human congenital stationary night blindness type 1 (CSNB1). CSNB1 is an X-linked recessive condition and is identified by a loss of the electroretinogram (ERG) b-wave while the...
Graft rejection; Diagnostic imaging; Postoperative care
The fourth hand transplant recipient in Louisville lost his graft at nine months post transplant from ischemia due to severe graft arteriopathy. Conventional imaging techniques and clinical measurements, including CT angiography and measurements of...
Congenital stationary night blindness 1 (CSNBl) is a genetic disorder characterized in humans by night blindness, low visual acuity and myopia. CSNB 1 is caused by defects in genes that are involved in signaling between photoreceptors and...
Supervisory control systems--Security measures; Automatic data collection systems--Security measures
This thesis describes the development of a prototype security hardened field device (such as a remote terminal unit) based on commodity hardware and implementing a previously developed security architecture. This security architecture has not been...
Long-term exposure to harmful carcinogens like benzo[a]pyrene (BaP) are linked to lung cancer. Benzo[a]pyrene diol epoxide (BPDE), the ultimate carcinogen produced by BaP bioactivation, is believed to play an important role in lung carcinogenesis....
Copper--Physiological effect; Copper in the body; Heart--Hypertrophy
Previous studies have shown that copper (Cu) supplementation at physiologically relevant levels reverses cardiac myocyte hypertrophy induced by phenylephrine (PE), and that this effect was VEGF-dependent. Yet, the amount of VEGF in the media was...
Public health administration--Kentucky; Patient advocacy--Kentucky
Background: One of the core functions of public health is to develop policies that support community and individual health. There are many historic examples in which public health practitioners have advocated successfully for policies that...
Sick--Personal narratives; Sick--Psychology; Sick--Biography--History and criticism; Narrative medicine
This dissertation uses a phenomenological and sociological lens to explore how non-fiction illness narratives help us understand how perception of the self is disrupted because of serious illness or injury. Specifically, I use the French...
Parkinson's disease--Treatment; Stem cells--Therapeutic use
Parkinson's disease (PD) is a hypokinetic movement disorder resulting from the
progressive neurodegeneration of the dopaminergic nigrostriatal system in the brain and
the resulting imbalance between dopamine and acetylcholine in the basal ganglia...
Parasites; Medical parasitology; Parasitic diseases
This thesis investigated infection dynamics of parasitic nematodes at both the population
and individual levels by exploring evolutionary and historical aspects of infection as well
as how host-parasite interactions influence virulence. In...
Farmers' markets--Kentucky--Louisville; African Americans--Nutrition; African American consumers--Kentucky--Louisville; Health promotion--Kentucky--Louisville--Citizen participation; Food--Social aspects
The purpose of this study is to obtain a better understanding of the interactions and the
social environment of the local farmers' markets, Fresh Stops, and Healthy in a Hurry
Corner Stores in West Louisville and East Downtown. This study will...
Transportation--Kentucky--History; Kentucky. Board of Internal Improvement--History
For a brief period of fifteen years, the Board of Internal Improvement occupied a place of prominence in the political and economic affairs of Kentucky. From its
creation in 1835, until the revision of the constitution in 1850, the board spent vast...
Chronic periodontitis is strongly associated with composition of the oral biofilm
occupying the gingival crevicular aspect of the tooth and its associated root. Some gram-negative,
"red complex" bacteria instigate periodontal bone loss in...
The purpose of this study was to investigate how various components of family literacy programs such as operational characteristics (enrollment procedure, hours of operation, time of class, curriculum selection, type of instruction, and age of...
Temple of Zeus (Olympia, Greece); Sculpture, Greek--Greece; Olympia (Greece : Ancient sanctuary)
Built during the Early Classical period, the Temple of Zeus at Olympia and its sculptural program presented many new ideas in Greek society. I will argue that the Temple, in particular its metopes depicting the twelve Labors of Herakles,...
Shakespeare, William, 1564-1616; Courtly love in literature
"It is in the south of France and at a very early period that we must look for the origin of the system of Courtly Love. Gathered about several small courts, there existed, as early as the eleventh century, a brilliant society, in which woman...
Inflammation is now recognized as an important factor in several age-related diseases such as arthritis, atherosclerosis, multiple sclerosis and diabetes. In each case, sub-clinical chronic inflammation occurs over years and leads to progressive...
In fulfillment of the thesis project requirement for the Master of Fine Arts Degree at the University of Louisville, I portrayed the role of Paulina in William Shakespeare's The Winter's Tale. The production was directed by Dennis Krausnick,...
Heuristic; Production management; Personnel management--Data processing
The Naval Surface Warfare Center wishes to create a task assignment schedule
with a minimal training cost for workers to raise their skills to the required levels. As the
number of workers, skills, and tasks increase, the problem quickly becomes...
College dropouts; Dropout behavior, Prediction of; Graduate students
More than a decade after the state of Kentucky enacted higher education reform that provided specific direction to the University of Kentucky and the University of Louisville, this research study sought to examine the effect of student...
