Background - Cranial cruciate ligament (CrCL) rupture in the canine stifle is a leading
cause of orthopedic lameness in the dog. Several corrective surgical procedures have
been developed to return dogs to pre-injury function following CrCL...
Wheelchairs--Design and construction; Dogs--Equipment and supplies; Dogs--Health; Veterinary physical therapy
Hind limb paralysis may occur in dogs for a variety of neurological or musculoskeletal reasons. For dogs with limited mobility their lack of ability to ambulate can have a great impact on their physical and mental health. Canine wheelchairs can...
Temple of Zeus (Olympia, Greece); Sculpture, Greek--Greece; Olympia (Greece : Ancient sanctuary)
Built during the Early Classical period, the Temple of Zeus at Olympia and its sculptural program presented many new ideas in Greek society. I will argue that the Temple, in particular its metopes depicting the twelve Labors of Herakles,...
Skeletal muscle is the most abundant tissue in our body that provides a structural framework and regulates important biological processes. It is also a primary reservoir of protein. Skeletal muscle maintains its structural and functional integrity...
The purpose of this dissertation was to demonstrate that a new method of direct intracellular energy delivery was effective in maintaining viability of in vitro Human Umbilical Vein Endothelial Cells (HUVECs) when exposed to chemical ischemia for...
Acrolein--Toxicology; Stem cells--Effect of pollution on
Acrolein is a common pollutant present in ambient air, automobile exhaust, and tobacco smoke. Previous studies show that exposure to acrolein increases cardiovascular disease risk. To determine whether acrolein affect cardiovascular regeneration,...
Gene therapy; Spinal cord--Wounds and injuries; Tissue engineering
The combination of viral mediated gene delivery, tissue engineering, and Schwann cell (SC) transplantation offer a promising strategy to enhance axonal regeneration and functional recovery following spinal cord injury (SCI). The rationale and...
Spinal cord--Wounds and injuries--Treatment; Physical therapy
Activity-based rehabilitation in the form of overground or body weight-supported treadmill (BWST) locomotor step training has become the most widely accepted therapy translated from preclinical animal research to spinal cord injury (SCI) patients....
Pancreatic beta cells are extremely vulnerable to the destruction of Reactive Oxygen Species (ROS). In both type 1 and type 2 diabetes ROS are involved in the loss of U+000DF-cells. We hypothesized that the deficiency in ROS detoxifying system of...
Pancreatic beta cells are extremely vulnerable to destruction by Reactive Oxygen Species (ROS). In type 1 diabetes and islet transplantation ROS are thought to be involved in the loss of beta cells. To test the role of antioxidant in islet...
Inflammation is now recognized as an important factor in several age-related diseases such as arthritis, atherosclerosis, multiple sclerosis and diabetes. In each case, sub-clinical chronic inflammation occurs over years and leads to progressive...
Bcl-2 proteins are major regulators of cellular responses to various apoptotic stimuli. Among them, overexpression of the anti-apoptotic BcI-2 protein BcI-xL modulates organelle-specific apoptotic pathways. To understand the mechanisms by which...
Diabetic cardiomyopathy (DCM) is a common complication leading to accelerated cardiovascular failure in diabetic patients. Even though the exact mechanism(s) behind this disease still remain unclear, research from several laboratories including our...
Background and significance: Even with the advent of direct bonding, decalcification remains a problem in orthodontics today. Glass ionomer cements have been used in dentistry for fluoride release for years and may have beneficial use in...
A combination of three techniques – high resolution micro computed tomography (micro CT) scanning, Archimedes-based volume fraction measurement and serial sectioning or milling – were used to determine the volume fraction, trabecular thickness,...
Fantasy fiction, American; Fantasy fiction, Japanese
This creative thesis follows the opening story arc to a larger fiction project in the genre of high fantasy fiction. Structurally and stylistically, by incorporating contemporary contributions to the genre from Japanese popular culture, this story...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 29. No. 37. but is actually Vol. 29. No. 40. This issue is four pages.
A small white, or light-colored, dog stands on its hind legs. Appears to be on a brick sidewalk next to a basement window. Title supplied by cataloger.
African Americans; African Americans--Education; African Americans--Social conditions; Louisville Municipal College for Negroes (Louisville, Ky.); Central High School (Louisville, Ky.); Kappa Alpha Psi Fraternity; African Americans--Employment;...
Oral history interview conducted with James Shively on December 18, 1978 by Dwayne Cox. Mr. Shively focuses largely on his education in Louisville, at Louisville Central High School and the Louisville Municipal College, in the 1930s and 1940s. He...