The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
A new procedure has been developed for determining
the location of the source of certain EEG discharges
given the measured surface potentials. The
source is modeled as a single current dipole with arbitrary
position and orientation, while the head...
The advent of larger storage spaces, affordable digital capturing devices, and an ever growing online community dedicated to sharing images has created a great need for efficient analysis methods. In fact, analyzing images for the purpose of...
Mucin 1 (MUC1) is a plasma membrane-bound glycoprotein that plays a protective role in corneal epithelial cells. Two full-length splice variants of MUCl: MUCl/B and MUCl/A, that differ by the inclusion of 27 bp from intron 1 and a SNP in MUCl/A,...
For complex classification systems, data is usually gathered from multiple sources of information that have varying degree of reliability. In fact, assuming that the different sources have the same relevance in describing all the data might lead to...
Optimal trajectory generation is an essential part for robotic explorers to execute the total exploration of deep oceans or outer space planets while curiosity of human and technology advancements of society both require robots to search for...
In this dissertation research, we aim to solve problems of two types of survival data, clustered survival data with potentially informative cluster size and sojourn time data. The methods for these two types of data are different. However, both...
Clustered longitudinal data is often collected as repeated measurements on subjects over time arising in the clusters. Examples include longitudinal community intervention studies, or family studies with repeated measures on each member. Meanwhile,...
The objective of this thesis is to develop computer programs for the dynamic analysis of structures. For a shear building two computer programs were developed: (1) Dynamic Analysis of a Shear Building within the Elastic Range and (2) the Dynamic...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 18. No. 48. but is actually Vol. 18. No. 53.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There are creases and small tears along the center of each page of this issue.
Condensed milk--Research; Milk--Research; Dried milk--Research; Milk as food
Although much work has been done in determining the nutritional values of different milks, all of it has been carried on at different times by various men, and there is no published data demonstrating the relative values derived from experiments...
"Regen-Kanon" is the fourth of six pieces or "sound images" in the orchestral cycle Spharen, composed by York Holler between 2001 and 2006. The first four movements, namely "Wolkengesang" ("Song of the...
This thesis is an investigation into the world of sixteenth-century Venice, encompassing a group of female portraits by artist Palma Vecchio. I utilized many primary and secondary sources concerning Renaissance society, including several which...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There are small portions missing along the sides of each page of this issue.
Thirty smokers were solicited from the Wichita, Kansas community via the newspaper and broadcast media for a stop-smoking project. The volunteers were assigned to one of two treatments: double smoking or a modification of Von Dedenroth's (1964)...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 32. No. 14. but is actually Vol. 32. No. 17. There is a crease across the center of each page that...