Rootkits are stealthy, malicious software that allow an attacker to gain and maintain control of a system, attack other systems, destroy evidence, and decrease the chance of detection. Existing detection methods typically rely on a priori knowledge...
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
Trees in cities--Kentucky--Louisville; Urban forestry--Kentucky--Louisville; Louisville (Ky.)--Environmental conditions
Trees in urban residential neighborhoods provide valuable ecosystem services. Urban trees also face threats from disturbances, such as storms. In 2008, the Urban Forest Effects model was used to estimate abundance and species composition of...
Item response theory; Goodness-of-fit tests; Monte Carlo method
Item response theory (IRT) is expanding to diverse research settings, without accompanying access to easily implemented model fit methods. One simple model fit approach involves x2/df ratios. However, its utility is not known across several...
Osteoporosis has become a growing health threat with rising social and economic consequences. The understanding of the relationship between bone mechanical strength and bone structural quality is important for the diagnosis of osteoporosis and the...
College graduates--Relocation; Educational attainment; Migration, Internal--United States
As state policymakers draw clearer connections between the college-level attainment of their residents and the corresponding economic and social benefits, there is great need for more data and information regarding the production and migration of...
This study explores four economic development theories – classical location theory, human capital theory, agglomeration economies theory and creative cities theory, and their effectiveness in explaining the spatial distribution of high tech...
Russia (Federation)--Politics and government, 1991-
Every state, regardless of its size, faces a problem of spatial organization and distribution of its power over territory, particularly in times of the formation of its statehood and the establishment of the system of governance. The...
Computational grids are some of the largest computer systems in existence today. Unfortunately they are also, in many cases, the least reliable. This research examines the use of redundancy with permutation as a method of improving reliability in...
Kentucky--History--1792-1865; United States--History--Civil War, 1861-1865--Causes
During the secession winter of 1860-61 the Commonwealth of Kentucky found itself caught in the middle of the great sectional controversy. With the Union's fate hanging in the balance Kentucky figured as a prominent player in the outcome of that...
This work develops a method of estimating peak daily streamflow, Qpeak, for Kentucky streams using daily average streamflow, Qave, data from the United States Geological Survey's (USGS) National Water Information System (NWIS) website. The purpose...
Aortic Valve Bypass surgery has found renewed interest to researchers due to its application in high-risk patients with severe aortic stenosis. This therapy consists of construction of a conduit containing a bioprosthetic or mechanical valve from...
A connected matching in a graph is a set of disjoint edges such that, for any pair of these edges, there is another edge of the graph incident to both of them. This dissertation investigates two problems related to finding large connected matchings...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There are small portions missing along the side of pages one and two of this issue.
African American men--Mental health; Depression in men; Depression, Mental--Social aspects
Background: In any given year depression affects as many as 121 million people worldwide and 20 percent or 19 million people in the U.S. suffer from at least one episode of depression during their lifetime. In the U.S., depression has a substantial...
This study focuses on the variation in structural response to synthetic ground motions derived from the latest attenuation models developed for the Central Eastern United States (CEUS) and used by the USGS to develop the latest edition (2008) of...
The Consumer and Industrial group of the General Electric Company (GE) allocates its shipping truckload to seventeen different trucking companies over 701 different routes from each of its nine terminals to 48 contiguous states. One of the...