Parkinson's disease--Treatment; Stem cells--Therapeutic use
Parkinson's disease (PD) is a hypokinetic movement disorder resulting from the
progressive neurodegeneration of the dopaminergic nigrostriatal system in the brain and
the resulting imbalance between dopamine and acetylcholine in the basal ganglia...
DNA microarrays--Statistical methods; Gene expression--Statistical methods
Data derived from gene expression microarrays are frequently used to identify candidate genes which can characterize and distinguish between two biological phenotypes. A key step in this process is the selection of an appropriate test statistic to...
Medical education; Medical students; Kentucky School of Medicine
Catalog for the Kentucky School of Medicine for 1885. Includes list of board of regents and faculty, program information, graduating class for 1894, and students enrolled for 1884. Printed on cover: Kentucky School of Medicine Twenty-Ninth Annual...
It has been shown that GSK3 β plays a critical role in the inflammation response by differentially regulating MyD88-dependent pro- and anti-inflammatory cytokines production in TLR4-stimulated innate immune cells. The work included in this...
Phase II clinical trial are generally single arm trial where a homogeneity assumption is placed on the response. In practice, this assumption may be violated resulting in a heterogeneous response. This heterogeneous or overdispersed response can be...
Alcoholic liver disease (ALD) ranks among the major causes of morbidity and mortality in the world and effects millions of patients each year. Progression of ALD is well characterized and is actually a spectrum of liver diseases, which progresses...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a tear down the center of each page of this issue.
The purpose of this study was to determine the effects of acute glutamine supplementation on maximal performance and recovery from high-intensity exercise. In a placebo-controlled, crossover study, seven (six males and one female) healthy subjects...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. A quarter of the first two pages of this issue is missing as well as significant other portions. The following six pages...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue is twelve pages. There are small portions missing along the top of each page of this issue. Almost half of...
Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) catalyze the detoxification and/or activation of aromatic and heterocyclic amine carcinogens by two pathways. This metabolism reaction can lead to the detoxification by Nacetylation, or...
Reperfusion of the ischemic lung causes pulmonary arteriolar vasoconstriction and reduces alveolar perfusion. Lung ischemia-reperfusion (IR) injury leads to platelet and leukocyte activation which could contribute to decreased alveolar perfusion...
School yearbooks; Schools; Students; University of Louisville--Students; Alumni & alumnae; University of Louisville--Alumni and alumnae; Student organizations; Universities & colleges; Medical students; Law students; College students;...
Yearbook published by the students of the University of Louisville, Louisville, Kentucky, 1909.
Medical education; Medical students; Kentucky School of Medicine
Catalog for the Kentucky School of Medicine for 1886. Includes list of board of regents and faculty, program information, graduating class for 1885, and enrolled students for 1885. Printed on cover: Kentucky School of Medicine Thirtieth Annual...
Integrins are major receptors for cell adhesion to the extracellular matrix, and play key roles in various cellular processes including adhesion, migration, proliferation and survival. Apart from developmental and physiological events, integrins...
A projected high penetration of battery electric vehicles (BEV s) in the market will introduce an additional load in the electricity grid. Furthermore, uncontrolled BEV charging from residential users will exacerbate the existing peak load during...
Medical education; Medical students; Louisville Medical College
Catalog for Louisville Medical college for 1878-1879. Includes list of board of trustees and faculty, program information, class list of 1877-1878, commencement information and list of graduates, and advertisements. Printed on cover: Annual...
Electroencephalography; Visual evoked response; Drug addicts--Research
In 2006 it was estimated by the Substance Abuse and Mental Health Service Administration (SAMHSA, 2007) that 19.9 million Americans used illicit drugs, computing to roughly 8.0 % of the United States population. In 2007, there were 2.1 million...
Modular hip implants are currently being used in total hip arthroplasty revision procedures because it is common to have little or no bone left in the proximal region of the femur and it is difficult to accurately size implants based off of...