Na,K-ATPase is essential for the regulation of cytoplasmic Na+ and K+ levels in lens cells. Insufficient Na,K-ATPase activity is associated with cataract formation. Based on earlier studies in which Src-tyrosine kinase inhibitors were found to...
The purpose of this dissertation was to demonstrate that a new method of direct intracellular energy delivery was effective in maintaining viability of in vitro Human Umbilical Vein Endothelial Cells (HUVECs) when exposed to chemical ischemia for...
DNA microarrays--Statistical methods; Gene expression--Statistical methods
Data derived from gene expression microarrays are frequently used to identify candidate genes which can characterize and distinguish between two biological phenotypes. A key step in this process is the selection of an appropriate test statistic to...
In recent years, a number of computational and statistical problems for identifying SNP-SNP interactions in high dimensional survival data have been studied, and several data mining approaches have been proposed. However, the relative performance...
Anxiety in children; Resilience (Personality trait) in children; Temperament in children; Child development
Anxiety is a common and debilitating disorder in children. Until recently, research in the field of child anxiety has focused on the identification of specific risk factors in the development of child anxiety. More recent studies have begun to...
Arrhythmia; Heart--Diseases; Heart beat; Heart conduction system
Introduction: Hyperhomocysteinemia (HHcy) is a pathological condition characterized by excessive levels of plasma homocysteine (Hcy). Patients with HHcy are reported to be at risk for arrhythmias like atrial fibrillation and sudden cardiac death...
Nuclear Factor of Activated T-cells (NFAT) is a calcium-responsive transcription factor that orchestrates immune response and cardiovascular development. NFAT is also present in neurons and glia from the Central Nervous System (CNS) where it...
This study of Mably’s works was undertaken because of the scant treatment thus far accorded the writings of a philosopher, important in his own century, and peculiarly interesting today in view of the present partial realization of many of his...
In some previous papers, feed forward configurations of realizing second order all pass transfer functions with complex poles by adding some configurations to a first order circuit are discussed. In this dissertation, the above idea extended to...
Crossover design is a type of longitudinal study with each subject receiving different treatments in different time periods. It has been used frequently in the pharmaceutical industry and other medical fields to investigate the safety and efficacy...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a tear down the center of each page of this issue and portions of pages one and five are very faded.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There are portions missing along the sides of each page of this issue.
The purpose of this project was to compare the accuracy and reliability of linear measurements made on 2D projections and 3D reconstructions using Dolphin 3D software (Chatsworth, CA) as compared to direct measurements made on human skulls. The...
The pulvinar is the largest nucleus of the human dorsal thalamus and is affected in a variety of brain disorders, such as schizophrenia. The experiments described in this dissertation elucidate key features of tecto-pulvino-cortical pathways as a...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 29. No. 43. but is actually Vol. 29. No. 45. This issue is four pages.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 32. No. 43. but is actually Vol. 32. No. 47.
The current status of our knowledge of synaptic plasticity comes largely from studies of the hippocampus and the context of learning and memory. We remain largely ignorant of plasticity in other neural systems and contexts. The molecular basis of...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 14. No. 36. but is actually Vol. 14. No. 38.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. An article has been clipped from the top corner of pages one and two of this issue.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a small tear from the center of pages one and two of this issue.