Pro-life movement--United States--Case studies; Rhetoric--United States; Abortion--United States
The purpose of this study is to consider the significance of rhetoric used by pro-life social movement organizations to frame the experience of abortion and to label those women who have participated in that experience. The study explores how...
Chapter 1 detailed the synthesis method of hydroxamate peptides derivatives of pentapeptide Ac-PHSXX\'-N-NH2 by solid phase hydroxamate peptide synthesis method. The glutamic acid/aspartic acid side chain was modified to hydroxamic acid by on resin...
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
Previous studies on the mechanistic induction of anti-tumor responses by IL-12 cytokine therapy have focused on the adaptive immune response, specifically the activation NK cells and T cells as the primary targets of IL-12 treatment. In contrast,...
Kentucky--Governor (1859-1862 : Magoffin); Kentucky--History--Civil War, 1861-1865; United States--History--Civil War, 1861-1865
This thesis seeks to understand Beriah Magoffin as Governor of Kentucky. Adding to the work begun by Michael T. Dues and Lowell H. Harrison during the 1960s and 1970s, this thesis fleshes out a man little studied in history. It addresses several...
This dissertation presents an analytical investigation that examined the seismic performance of steel stud backed and Concrete Masonry Units (CMU) backed masonry veneer wall systems, under in and out - of - plane loads, in medium rise building...
Introduction: Although orthodontics can correct a variety of dental and skeletal
malocclusions, research has shown an increased risk of enamel demineralization leading
to white spot lesions (WSLs). The purpose of this study was to compare the...
Recent advances in understanding the molecular mechanisms of mutagenesis indicate that most mutations are dependent on the activity of translesion synthesis DNA polymerases. The impact of reducing the level of these polymerases on mutagenesis and...
Public administration--Decision making; Political planning--United States--Case studies; Bankruptcy--United States
The purpose of this study is to analyze two Congressional decisionmaking models and two policymaking models to identify which provides the strongest explanation of the bankruptcy reform process between 1997 and 2005. The two models of Congressional...
Tallis, Thomas, ca. 1505-1585. Lamentations, no. 1; Tallis, Thomas, ca. 1505-1585. Lamentations, no. 2; Byrd, William, 1542 or 3-1623. De Lamentatione Hieremiae;
Movement through pitch space in the Common Practice Period is generally acknowledged as being structured on the fifth relation, whereas movement through the pitch space of the highly chromatic music of the nineteenth century is thought of as being...
In the United States substance abuse takes a toll that is costly in both economic and human terms. In 2005 we paid 467.7 billion dollars to address the consequences of substance abuse, and each year we have lost an estimated 537,000 of our fellows...
Nuclear Factor of Activated T-cells (NFAT) is a calcium-responsive transcription factor that orchestrates immune response and cardiovascular development. NFAT is also present in neurons and glia from the Central Nervous System (CNS) where it...
Church architecture--Italy; Ambrose, Saint, Bishop of Milan, d. 397; Italy--History--To 476
This thesis argues that the architecture of the churches of northern Italy that were constructed during the fifth and sixth centuries reflected the influence and vision of Ambrose, bishop of Milan (374-397), whose spiritual authority, theologically...
Slavery--Political aspects--Kentucky; Kentucky--History--Civil War, 1861-1865
In his 1926 study of the Civil War era in Kentucky, southern historian E. Merton Coulter repeated the old saying that Kentucky was the only state to secede after Appomattox. In an over-simplification of the process, most historians have seen harsh...
Previous research on organizational mergers has found that such a business activity bears an effect upon the structural and cultural foundations of organizations. Whether combining intellectual resources or capital, mergers combine workforces that...
20S proteasome, essential component of protein degradation mechanism, is important to maintain homeostasis. Its malfunctions have been associated with several pathological conditions. This study presents an extensive study of murine cardiac 20S...
Tobacco smoke is a strong and independent risk factor for several chronic systemic diseases and also increases susceptibility to a multitude of bacterial infections, including periodontal infections. Periodontitis is a chronic inflammatory disease...
Online organizations are always in search for innovative marketing strategies to better satisfy their current website users and lure new ones. Thus, recently, many organizations have started to retain all transactions taking place on their website,...
Heart--Hypertrophy; Hydrogen sulfide--Therapeutic use
Background: Although matrix metalloproteinase (MMPs) and tissue inhibitor of metalloproteinase (TIMPs) play a vital role in tumor angiogenesis and TIMP-3 causes apoptosis, their role in cardiac angiogenesis is unknown. Interestingly, a disruption...
Inflammatory bowel disease (IBD) is a chronic autoimmune disorder that is subdivided into Crohn's disease (CD), ulcerative colitis (UC), and indeterminate colitis (IC). Epidemiological studies have proven that genetic variation increases...