Orbital shakers are commonly used in the cell culture industry due to their ease of use, but the fluid dynamics of this system have not been extensively modeled as the system is difficult to quantify analytically. It is desirable to understand how...
INTRODUCTION: Attention Deficit/Hyperactivity Disorder (ADHD) is a disorder that is prevalent throughout the world. It is believed that 5% of school aged children suffer from ADHD, with some estimates indicating as high as 10% may suffer from the...
Gold nanoparticles (AuNPs) have attracted enormous attention in the field of nanotechnology for applications such as, immunoassay, drug delivery, contrast enhancement and tumor therapy. The typical range of gold nanoparticles varies from 1– 150...
Myocardial infarction; Glucose--Metabolism; Mitochondrial DNA
Heart failure is a leading cause of morbidity and mortality in the USA. During the development of heart failure, many cardiac parameters change at the same time including fuel metabolism, oxidative stress and mitochondrial function. Each of these...
This work presents a novel comprehensive effort to understand the fluid dynamics within orbiting dishes and the effects of the resulting oscillating fluid flow on shear and endothelial cellular responses within the dishes. It is well documented...
Dynamic analysis and parameter identification of a single mass elastomeric isolation system represented by Maxwell model is examined using both analytical and experimental approaches in this dissertation. Influences that the stiffness and damping...
This dissertation describes (1) size-dependent electrochemical oxidation/stripping of gold and silver nanoparticles (NPs), (2) alloying of copper with gold nanoparticles at underpotential deposition potentials, (3) electrochemical characterization...
The properties of gold nanoparticles (GNP) holds promising potential for drug delivery, diagnostics, plasmonic photothermal therapy of diseases, electronics, catalysis, and photovoltaics (Liu et al., 2006; Huang et al., 2003; Thompson, 2007;...
Air void structure in hardened concrete is critical to its durability. This project mainly focuses on investigating the air void system in hardened concrete with the microscopic analysis Linear Traverse Method specified by ASTM Specification...
Electromyography; Spinal cord--Wounds and injuries
Introduction: Approximately 12,000 new cases of spinal cord injury (SCI) are reported each year in the US. Currently, the most widely used method of assessing the recovery of voluntary capability after spinal cord injury is the American Spinal...
Nanoparticles are a class of materials that exhibit unique physical and chemical properties compared to those of the same material at the bulk scale. One method of enhancing the thermal conductivity, and hence the heat transfer coefficient, of a...
Soon after the atomic theory was established, it was found that the plant uses as sources of food not only the air and water, but also different constituents of the soil, dissolved in the soil moisture—the mineral nutrients. Ashes of different...
The Knudsen pump works on the principle of thermal transpiration. As a result of requiring a thermal gradient, channel hydraulic diameter smaller than the mean free path of the gas being pumped, and having no moving parts, the Knudsen pump features...
T cells; Disease susceptibility; Lupus; Sex factors in disease
Females are more susceptible to autoimmune disease than males. In several mouse models of disease, castration of males exacerbates disease while androgen treatment ameliorates disease. These data suggest hormones can have an influence on disease...
Optimizing queries in a distributed database is quite difficult. This work proposes defining new generalized quantifiers which operate on sets rather than tuples. These quantifiers would allow for easier optimization in a horizontally distributed...
This thesis looks at the optimization of fluid flow and mass transfer using computational fluid dynamics (CFD) in a micro fluidic coulter counter. CFD will be used to solve equations of fluid flow and mass transfer to see how molecules within the...
Through differential display PCR, Munc13-3 was identified as a gene whose relative expression in the visual cortex corresponds to critical period plasticity. Expression of the gene was low at the peak of the critical period and expression was high...
Hemolysis (red cells lysis) caused by fluid stresses in flows within hypodermic needles, blood pumps, artificial hearts and other cardiovascular devices, is one of the major concerns during the design and use of cardiovascular or blood-processing...
This thesis begins by reviewing human N-acetyltransferases (Chapter I), then outlines experiments involving human hepatocytes and rat N-acetyltransferases (Chapters II-V). These experiments facilitated the development of a dissertation project...
In this dissertation, standardized methods for measuring electron emission (EE) from nanostructured materials are established. Design of an emitter array platform, synthesis and nanomanipulation of different types of are successfully conducted....
