Indians of North America--Kentucky--Bullitt County--Antiquities; Excavations (Archaeology)--Kentucky--Ashworth Rockshelter site; Ashworth Rockshelter site (Ky.)
Reinvestigation of a National Register property, the Ashworth Rockshelter (15BU236), northeast of Shepardsville, Bullitt Co., Kentucky, revealed stratified Early Archaic through Mississippian components (ca. 7900 B.C.-1500 A.D.). Primary occupation...
Computer vision; Pattern recognition systems; Human face recognition (Computer science)
Humans have the uncanny ability to perceive the world in three dimensions (3D), otherwise known as depth perception. The amazing thing about this ability to determine distances is that it depends only on a simple two-dimensional (2D) image in the...
Human adult olfactory epithelium contains neural progenitors (hONPs) which replace damaged cellular components throughout life. Methods to isolate and expand the hONPs have been developed in our laboratory. In response to morphogens, the hONPs...
Estimating and analysis of deformation, either rigid or non-rigid, is an active area of research in various medical imaging and computer vision applications. Its importance stems from the inherent inter- and intra-variability in biological and...
This study expands our efforts to make a new class of Pt (II) compounds analogous to cisplatin and its derivatives using sterically hindered ligands. Pt compounds in this series have been synthesized using specially designed pyridine and...
Dialectical behavior therapy; Women prisoners--Rehabilitation; Women prisoners--Psychology; Women prisoners--Mental health services; Women prisoners--Mental health
This dissertation examines the effectiveness of a partial skills group component of Dialectical Behavior Therapy (DBT) in female prison inmates. DBT is an evidence-based comprehensive treatment which addresses emotional reactivity, impulsivity and...
Drug delivery systems; Curcumin--Therapeutic use--Administration
Curcumin, a plant derived compound has shown significant potency against various chronic diseases like cancer in cell culture and animal studies. However, the introduction of this compound into clinical setting is limited by its poor oral...
Various vision tasks are usually confronted by appearance variations due to changes of illumination. For instance, in a recognition system, it has been shown that the variability in human face appearance is owed to changes to lighting conditions...
Spinal cord--Wounds and injuries--Treatment; Physical therapy
Activity-based rehabilitation in the form of overground or body weight-supported treadmill (BWST) locomotor step training has become the most widely accepted therapy translated from preclinical animal research to spinal cord injury (SCI) patients....
Mixed-effects model is an efficient tool for analyzing longitudinal data. The random effects in mixed-effects model can be used to capture the correlations among repeated measurements within a subject. The time points are not fixed and all...
Pancreatic islet transplantation is a very promising treatment for type I diabetes. Many clinical trials have failed due to early islet loss and immune rejection. Reactive oxygen species (ROS) have been demonstrated to be involved in graft damage...
Pancreatic beta cells are extremely vulnerable to destruction by Reactive Oxygen Species (ROS). In type 1 diabetes and islet transplantation ROS are thought to be involved in the loss of beta cells. To test the role of antioxidant in islet...
20S proteasome, essential component of protein degradation mechanism, is important to maintain homeostasis. Its malfunctions have been associated with several pathological conditions. This study presents an extensive study of murine cardiac 20S...
Complement, an early recognition system of innate immunity that senses local tissue damage and infection, cross-talks with and regulates other signaling systems, including Toll-like receptor (TLR) pathways. In the context of periodontitis,...
Green tea--Health aspects; Green tea--Therapeutic use; Polyphenols--Physiological effect; Drug delivery systems; Lungs--Cancer--Treatment
Green tea polyphenols (GTPs) are gaining increasing attention because of their potential anti-tumor effects. However, poor oral bioavailability limits their efficacy in vivo. In this dissertation, two hypotheses were tested: 1) GTPs administered...
Chlamydia trachomatis is an obligate intracellular pathogen that utilizes a type III secretion system to enter mammalian cells and establish an intracellular niche. TARP, the translocated actin recruitment protein, is a chlamydial invasion protein...
Sick--Personal narratives; Sick--Psychology; Sick--Biography--History and criticism; Narrative medicine
This dissertation uses a phenomenological and sociological lens to explore how non-fiction illness narratives help us understand how perception of the self is disrupted because of serious illness or injury. Specifically, I use the French...
Enzymatic hydrolysis is the most common method of producing fermentable sugars from lignocellulosic biomass. Limitations to this step include the high cost of enzymes, and the time required to process the biomass. To increase the throughput and...
Freshwater mussels--Ecology; Freshwater mussels--Blue River (Ind.)
This study assessed life history components for the elephantear freshwater mussel, Elliptio crassidens (Lamarck, 1819). The main focus of this study was to determine the suitability of various fish species as a host for E. crassidens and to...
Representing the complex data in a concise and accurate way is a special stage in data mining methodology. Redundant and noisy data affects generalization power of any classification algorithm, undermines the results of any clustering algorithm and...
