United States. Resource Conservation and Recovery Act of 1976; Brownfields--United States
Public investment and interest into brownfields has increased markedly in the past two decades. However, scholarship has not kept pace with this growth. Every state in the U.S. has created a brownfields program to deal with the presence of these...
Senile dementia; Nursing home patients--Mental health; Anxiety in old age; Depression in old age
Dementia, depression, and anxiety are the most common psychiatric disorders among long-term care residents and, because dementia is associated with behavioral problems that can be difficult to manage, the growing number of long-term care residents...
Dehydroepiandrosterone (DHEA) is a C-19 adrenal steroid and the most abundant circulating hormone in humans. Since circulating levels decline in late adulthood, treatment of humans with DHEA has been suggested to have beneficial health effects....
Leopold, Aldo, 1886-1948; Naturalists--United States--Biography; Wildlife conservation--Study and teaching (Higher); Ecology--Study and teaching (Higher)
This historic case study addressed the issue of the lack of citizen action toward environmentally responsible behavior. Although there have been studies regarding components of environmental responsible behavior [ERB], there has been little focus...
Alcoholic liver disease (ALD) is a serious concern for the world's population. It is one of the leading causes of death and is also a huge economic burden. The biochemical mechanisms responsible for ALD are incompletely understood, therefore there...
It has been shown that GSK3 β plays a critical role in the inflammation response by differentially regulating MyD88-dependent pro- and anti-inflammatory cytokines production in TLR4-stimulated innate immune cells. The work included in this...
Monophosphoryl Lipid A (MPLA), a derivative of LPS endotoxin, is a TLR4 agonist that displays as little as 0.1-1% as much toxicity as its parent molecule while retaining immunostimulatory properties. We discovered that MPLA activates a TRIF-biased...
This project investigated the effect of hypothermia on the monocyte response with the goal of understanding, which intracellular processes are affected by hypothermia leading to differences in cytokine secretion. A better understanding of the...
The vaccinia virus complement control protein (VCP) is involved in the modulation of the host inflammatory response during vaccinia virus infection. It possesses the ability to inhibit both classical and alternative pathways of complement...
The purpose of this study was to assess the effects of short-term high-intensity resistance training on time to exhaustion at maximal aerobic output. It was hypothesized that 2 weeks of training will induce improvements in performance at maximal...
Chlamydia trachomatis is an obligate intracellular pathogen that utilizes a type III secretion system to enter mammalian cells and establish an intracellular niche. TARP, the translocated actin recruitment protein, is a chlamydial invasion protein...
Band directors--Attitudes; High school principals--Attitudes; Bands (Music)--Instruction and study
The purpose of this study was to survey secondary school administrator and band director perceptions regarding the implementation of Kentucky's Core Content for Assessment 4.1 (CCA 4.1) in Music in the band programs at their schools. Secondary...
Indians of North America--British Columbia; Literacy--British Columbia--Case studies
This dissertation examines the literacy practices of a group of First Nations women who live in British Columbia and whose jobs entail the production and dissemination of texts which reflect the local, Carrier, culture. In this qualitative study of...
N-acetyltransferase 1 (NAT1) is a phase II metabolic enzyme responsible for the biotransformation of aromatic and heterocyclic amine carcinogens such as 4-aminobiphenyl (ASP). NAT1 catalyzes N-acetylation of arylamines as well as the 0-acetylation...
Monoclonal antibodies directed toward tumor associated antigens are FDA approved anticancer reagents used commonly in the clinic. Administered antibodies initiate tumor cell death through several mechanisms. Improving immune mediated mechanisms,...
Digital control systems; Computer security; Process control--Computer programs; Supervisory control systems--Security measures
Supervisory control and data acquisition (SCADA) systems are networked control systems used in many critical infrastructure areas such as power water and transportation. Many of these systems continue to use legacy field devices that lack cyber...
We are more likely to "hurt the one's we love" than we are complete strangers (cf. R. Miller, 1991, 1997). Early in dating relationships, partners appear to me more likely to manage their impressions to present themselves as better than...
Recent advances in understanding the molecular mechanisms of mutagenesis indicate that most mutations are dependent on the activity of translesion synthesis DNA polymerases. The impact of reducing the level of these polymerases on mutagenesis and...
Genes in folate metabolizing pathway are responsible for modulating key enzymes in folate metabolisms necessary for DNA synthesis and repair and influence DNA methylation. Irregularity in DNA methylation may modify tumor phenotype response to...
Heart--Diseases--Patients--Rehabilitation; Data mining
The purpose of this paper is to examine the process of text mining and using the results to show the possible benefits of cardiopulmonary rehabilitation. The 555 patients enrolled in the study were receiving inpatient cardiopulmonary...
