Ribosomal biogenesis failure may contribute to neurodegenerative diseases, while its excessive activation has been shown to drive tumor growth. As ribosomal production is initiated and regulated by the Pol1-mediated transcription of rRNA genes in...
Wheelchairs--Design and construction; Dogs--Equipment and supplies; Dogs--Health; Veterinary physical therapy
Hind limb paralysis may occur in dogs for a variety of neurological or musculoskeletal reasons. For dogs with limited mobility their lack of ability to ambulate can have a great impact on their physical and mental health. Canine wheelchairs can...
Among gynecological malignancies, carcinoma of the cervix is the leading cancer type worldwide. Conversely, vaginal tumors account for an incidence of approximately 1-2% of lower genital tract malignancies. Interestingly, the major shared risk...
Protein C (PC) is an important anticoagulant, antithrombotic, and antiinflammatory in blood plasma. PC deficiency can lead to severe venous thrombotic events, including lung embolism, stroke, and heart attack. In the body, PC is activated only when...
Metastasis is a complex process requiring directed migration of metastatic cells to favorable microenvironments. Increased CXCR4 expression has been implicated in more invasive, aggressive and metastatic tumor phenotypes and poor patient survival...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. Pages one and eight of this issue are very faded.
Cortical and tectal inputs to the caudal LPN in the rat were examined using anatomical and physiological techniques. Pyramidal cells in layer 6 of the visual cortex and wide-field vertical cells in the stratum opticum of the superior colliculus...
A combination of three techniques – high resolution micro computed tomography (micro CT) scanning, Archimedes-based volume fraction measurement and serial sectioning or milling – were used to determine the volume fraction, trabecular thickness,...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a tear down the center of each page of this issue.
Many species of fungi undergo a dimorphic transition to switch from a unicellular yeast-like growth form to a filamentous growth form. Ustilago maydis undergoes such a transition, in response to successful mating events and subsequent host cues, to...
Mucin 1 (MUC1) is a plasma membrane-bound glycoprotein that plays a protective role in corneal epithelial cells. Two full-length splice variants of MUCl: MUCl/B and MUCl/A, that differ by the inclusion of 27 bp from intron 1 and a SNP in MUCl/A,...
Parking garages--Automation; Parking garages--Design and construction
Automated vehicle storage/retrieval system (AVS/RS) technology is relatively new. It has been applied successfully in several European facilities in 1990s. AVS/RS is a flexible system that is a viable alternative to automated storage/retrieval...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue is twelve pages. There are significant portions missing along the bottom of pages nine, ten, eleven, and...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a tear down the center of each page of this issue.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 31. No. 48. but is actually Vol. 31. No. 39.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There are small portions missing along the sides of each page of this issue and page one was duplicated in the microfilm...
Congenital stationary night blindness 1 (CSNBl) is a genetic disorder characterized in humans by night blindness, low visual acuity and myopia. CSNB 1 is caused by defects in genes that are involved in signaling between photoreceptors and...
Arsenic--Physiological effect; Cardiovascular system--Diseases; Liver--Effect of arsenic on; Arsenic--Toxicology
Chronic arsenic exposure is associated with increased cardiovascular disease (CVD). Prenatal arsenic exposure at 49 ppm arsenic accelerates atherosclerosis underlying CVD in ApoE-/- mice, but the mechanism is unknown. This dissertation examines the...
The secondary visual pathway, from the retina through the superior colliculus and pulvinar nucleus has been linked to spatial attention (Snow et aI., 2009; Arend et aI., 2008) movement planning and motor response to visual stimuli (Wilke et aI....
Archaeologists use soil analysis to detect chemicals, like phosphate, to indicate areas of anthropogenic activity. Phosphate detection is a multi-step process, which makes standard techniques time consuming. Kinetic studies decreased the analysis...
