Standard regularity assumptions for regression models are not satisfied in segmented regression models with an unknown change point, and consequently standard asymptotic results and inferential methods for confidence estimation are not applicable....
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue is twelve pages and is made up of the normal eight pages with an additional four page section called The...
A class of RC active filters in which the DC offset of the operational amplifier (op-amp) is completely absent from the filter output [1]. Individual filter configurations (Low Pass, High Pass, Band Pass, Band Stop, All Pass) are discussed and...
The advent of larger storage spaces, affordable digital capturing devices, and an ever growing online community dedicated to sharing images has created a great need for efficient analysis methods. In fact, analyzing images for the purpose of...
Heart--Hypertrophy; Hydrogen sulfide--Therapeutic use
Background: Although matrix metalloproteinase (MMPs) and tissue inhibitor of metalloproteinase (TIMPs) play a vital role in tumor angiogenesis and TIMP-3 causes apoptosis, their role in cardiac angiogenesis is unknown. Interestingly, a disruption...
When observers view a naturalistic (l/f) broadband image, the various spatial components present in the image stimulate many detecting-mechanisms that suppress each other. This suppression is anisotropic, being relatively greater for mechanisms...
Heart--Diseases--Diagnosis; Diagnostic imaging; Magnetic resonance imaging; Imaging systems in medicine
Many cardiac diseases, such as myocardial ischemia, secondary to coronary artery disease, may be identified and localized through the analysis of cardiac deformations. Early efforts for quantifying ventricular wall motion used surgical implantation...
No current microfabrication technique exists for producing room-temperature, high-precision, point-to-point polymer nanofibers in three dimensions. Producing rounded structures in a third dimension is particularly difficult to accomplish with...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. Should be Vol. 8. No. 9. but the masthead was not updated and the mistake was not accounted for in the following issue.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 18. No. 34. but is actually Vol. 18. No. 45. There is a significant portion missing from the bottom...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 18. No. 48. but is actually Vol. 18. No. 53.
Wind energy conversion systems; Wind power--Technological innovations; Wind power--Research
This thesis proposes a new Maximum Power Point Tracking (MPPT) algorithm employed in Wind Energy Conversion Systems (WECS). One of the major issues discussed in the literature concerning HCS is its inefficiency in detecting the peak power when...
Recent advances in high throughput methodologies offer researchers the ability to understand complex systems via high dimensional and multi-relational data. One example is the realm of molecular biology where disparate data (such as gene sequence,...
Hypertension--Genetic aspects; Coronary heart disease--Genetic aspects; African Americans--Health and hygiene
Cardiovascular diseases, including hypertension, are the leading causes of death in
the United States. African-Americans carry the highest burden of disease with 32% of
adults with hypertension. Blood pressure (BP) dipping, defined as a drop of>...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a portion missing from the bottom of the first and second pages of this issue.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. Each page of this issue is extremely faded.