The discovery of carbon nanotubes and subsequently graphene has led to an interest in carbon materials as sensing elements due to their unique properties. Graphene is a 2-dimensional material that has a large surface area that can be exposed to...
Arsenic--Physiological effect; Cardiovascular system--Diseases; Liver--Effect of arsenic on; Arsenic--Toxicology
Chronic arsenic exposure is associated with increased cardiovascular disease (CVD). Prenatal arsenic exposure at 49 ppm arsenic accelerates atherosclerosis underlying CVD in ApoE-/- mice, but the mechanism is unknown. This dissertation examines the...
Community college students--Transfer; Academic achievement; College attendance
The reverse transfer literature contains studies investigating the demographic characteristics of postsecondary students that attended a community college after attending a four-year institution, and their proportion in the community college...
Community college students--Kentucky; Transfer students--Kentucky; Academic achievement--Kentucky; College attendance; University of Louisville; Jefferson Community and Technical College
More students now begin their postsecondary education at the two-year college level with the intention of transferring to earn a bachelor's degree, making the transfer function more important. Recent government mandates in Kentucky brought about...
Na,K-ATPase is essential for the regulation of cytoplasmic Na+ and K+ levels in lens cells. Insufficient Na,K-ATPase activity is associated with cataract formation. Based on earlier studies in which Src-tyrosine kinase inhibitors were found to...
The purpose of this research project is to evaluate the feasibility of interhospital patient transfers (within a hospital corporation referred to as NESW Hospital Co.) as a means of reducing emergency department overcrowding. Customer satisfaction...
In blood coagulation, the serine protease thrombin is a multifaceted enzyme that interacts with multiple proteins. Thrombin utilizes two anion binding exosites (ABE-I and II) to supplement binding to fibrinogen and to the platelet receptor GpIbα,...
Understanding of the band structure of the new nano materials is essential to have a deeper insight into their optical and electrical properties. Along with the existing techniques used for characterization of nano-materials, it is also important...
The immune system is of profound importance for host survival due to its ability to clear many acquired diseases. In case of infections and cancer, disease arises due to under-performance of immune system. Whereas in autoimmunity and...
The lipid aldehydes, 4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are reactive α,β-unsaturated aldehydes generated during the peroxidation of lipids and are implicated in the pathogenesis of several oxidative-stress mediated diseases,...
Surface active agents; Rendering industry--Waste disposal; Air filters
Meat is a major component of the diet of an American. However, humans do not consume one-third to one-half of each animal raised for their needs. The leftover materials are subjected to processing in the meat rendering industry. The rendering...
Oxygen is critical to aerobic metabolism, but hyperoxia is cytostatic and cytocidal. The precise mechanisms involved in hyperoxic cell injury remain incompletely understood although there is substantial support for the possibility that hyperoxia...
Nosocomial infections; Catheterization--Complications; Drug resistance in microorganisms
Catheters represent an essential part of the management of critically and chronically ill patients. However, their use is often plagued by catheter related blood stream infections (CRBSIs), which are associated with increased morbidity, hospital...
This research project describes the application of a master/slave configuration of processors to study a comparison of alternative material handling configurations for automated manufacturing. Such a study usually requires a large number of...
The current status of our knowledge of synaptic plasticity comes largely from studies of the hippocampus and the context of learning and memory. We remain largely ignorant of plasticity in other neural systems and contexts. The molecular basis of...
Mosquitoes as carriers of disease; Dengue viruses; Mosquitoes--Physiology
In the course of their life cycle, mosquitoes undergo an ontogenetic niche shift; immature larval development occurs within an aquatic habitat from which adult mosquitoes subsequently disperse into the terrestrial environment. While adult female...
T cells; Disease susceptibility; Lupus; Sex factors in disease
Females are more susceptible to autoimmune disease than males. In several mouse models of disease, castration of males exacerbates disease while androgen treatment ameliorates disease. These data suggest hormones can have an influence on disease...
In the present study, we report the synthesis of thermally stable mesoporous gallium oxide and novel gallium-niobium mixed oxides employing Evaporation Induced Self-Assembly (EISA), Self-Assembly Hydrothermal-Assisted (SAHA) and Self-Assembly...
Few previous studies have compared microbial communities in subterranean and surface environments. Chemical analyses used to characterize the surface and cave microbial environments indicated limited exchange between surface and subsurface waters....
Assessing the functionality of the endothelium can provide insight into the initiation and formation of arterial diseases. One of the most important functions of the endothelial layer is its permeability. The integrity of the cell monolayer and its...
