Epithelial Ovarian cancer (EOC) is the leading cause of gynecological cancer death in the USA. Recurrence rates are high after front-line platinum chemotherapy and most patients eventually die from platinum-resistant disease. P53 plays an important...
Background: Helicobacter pylori (Hp) establishes life-long gastric infection in billions of humans, and is often responsible for diseases such as peptic ulcer and gastric cancer. Cumulative actions of genetic drift and natural selection over...
Long-term exposure to harmful carcinogens like benzo[a]pyrene (BaP) are linked to lung cancer. Benzo[a]pyrene diol epoxide (BPDE), the ultimate carcinogen produced by BaP bioactivation, is believed to play an important role in lung carcinogenesis....
Nerves--Regeneration; Spinal cord--Wounds and injuries--Treatment
These studies set out to identify strategies to rescue and repair the adult nervous system. First, we investigated the role of ciliary neurotrophic factor (CNTF) in 5HT1A receptor-induced neurogenesis in the rodent brain. Systemic treatment with an...
A combination of three techniques – high resolution micro computed tomography (micro CT) scanning, Archimedes-based volume fraction measurement and serial sectioning or milling – were used to determine the volume fraction, trabecular thickness,...
c-Myc dysregulation is one of the most common abnormalities found in human cancer. MicroRNAs (miRNAs) are functionally intertwined with the c-Myc network as multiple miRNAs are regulated by c-Myc, while others directly suppress c-Myc expression. In...
Spinal cord--Wounds and injuries; Stretch (Physiology)
An increasing amount of healthcare resources is used for the treatment and prevention of contractures in patients with spinal cord injury (SCI), with stretch and passive movements remaining the most prominent intervention methods. The results of...
Atmospheric nitrous oxide; Nitric acid; Rain and rainfall--Environmental aspects
Having been born and brought up in China, an empire, where the people are utterly ignorant of the vital importance of a good system of public water supply, and having decided to take chemistry as my profession, I feel intensely interested in the...
Medical care, Cost of--Research--United States; Poor-- Medical care--United States
This thesis uses data from the 2002 Medical Expenditure Panel Survey in a quantitative examination of the capacity of the labor market in the United States to provide employment to the poor which enables them to afford health care. The...
Cancer accounts for nearly one-quarter of deaths in the United States, exceeded only by heart diseases. Despite the development of various strategies to treat cancer, it remains one of the most deadly diseases worldwide due to the limited effects...
Dialectical behavior therapy; Women prisoners--Rehabilitation; Women prisoners--Psychology; Women prisoners--Mental health services; Women prisoners--Mental health
This dissertation examines the effectiveness of a partial skills group component of Dialectical Behavior Therapy (DBT) in female prison inmates. DBT is an evidence-based comprehensive treatment which addresses emotional reactivity, impulsivity and...
Youth--Employment; Teenagers--Health and hygiene; Industrial safety; Safety education, Industrial
Teenaged workers are twice as likely to be injured on the job as adult workers, and face a
number of differences developmentally and psychosocially that present challenges for
their safety at work. Little research has focused on the tasks that...
The area of total coloring is a more recent and less studied area than vertex and edge coloring, but recently, some attention has been given to the Total Coloring Conjecture, which states that each graph's total chromatic number xT is no greater...
Writing centers; English language--Rhetoric--Study and teaching (Higher); Oral reading
Reading aloud in writing center sessions is a common practice, one that is both under-studied and under-theorized. In an attempt to begin to address this gap, this dissertation conducts an empirical analysis of three different methods of reading...
The aim of this study was to determine if playing 5 soccer matches in 4 weeks after 8 weeks of strength, conditioning and soccer training further improves aerobic and anaerobic performances. Ten college soccer players (20.1 ± 1.2 yr) completed...
English language--Rhetoric--Study and teaching; College prose--Evaluation; Interaction analysis in education; Education, Higher--Computer-assisted instruction; Distance education--Computer-assisted instruction
Current scholarship indicates an increase in the use of asynchronous electronic
formats by writing instructors and tutors responding to student writing. However, little
research has been done to understand the ways in which different formats affect...
The works of Maurice Duruflé (1902-1986) comprise a small but significant body of sacred music and compositions for organ, yet they have received little serious analytical attention. The present study examines an early organ work, the Prélude,...
Nanoparticles are a class of materials that exhibit unique physical and chemical properties compared to those of the same material at the bulk scale. One method of enhancing the thermal conductivity, and hence the heat transfer coefficient, of a...
Tobacco smoke is a strong and independent risk factor for several chronic systemic diseases and also increases susceptibility to a multitude of bacterial infections, including periodontal infections. Periodontitis is a chronic inflammatory disease...
Breast--Cancer--Diagnosis; Medical screening; Breast--Radiography; Mobile hospitals
This study used the de-identified breast cancer screen data which recorded the
information of 58231 screens and 22534 participants with different background. The
analysis of disparities on age, ethnic, health insurance and screen location has been...