The acetogenin annonacin, from the tropical annonaceous plant Annona muricata, is a lipophilic, mitochondrial complex I inhibitor reported to be more toxic than rotenone to mesencephalic neurons. The temperate annonaceous plant Asimina tri/oba...
4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are highly reactive á,â-unsaturated aldehydes. 4-HNE and acrolein are generated in vivo as products of lipid peroxidation. These aldehydes are implicated in the onset of several diseases...
This research was performed to establish the feasibility of using Direct Metal Deposition (DMD) technology to deposit nickel powder to a nickel substrate. The substrate is electrodeposited pure nickel, and the material to be deposited is Metco...
National Board for Professional Teaching Standards (U.S.); Academic achievement--Kentucky; Teachers--Certification--Kentucky; Teacher effectiveness--Kentucky
This dissertation focused on the link between quality teaching and its potential impact on student achievement. National Board Certification is used to represent quality teaching and student achievement is measured by the Kentucky Core Content...
The fundamental question of the exact nature of the role played by TNF in the failing myocardium remains one of contention. Many preclinical studies have demonstrated beneficial effects with TNF antagonism and recently the dichotomous role played...
Three-dimensional imaging in medicine; Diagnostic imaging; Dental care
CBCT in endodontics demonstrates anatomic features in 3D that intraoral, panoramic, and cephalometric images cannot. CBCT units reconstruct the projection data to provide interrelational images in three orthogonal planes (axial, sagittal, and...
Heart--Hypertrophy; Hydrogen sulfide--Therapeutic use
Background: Although matrix metalloproteinase (MMPs) and tissue inhibitor of metalloproteinase (TIMPs) play a vital role in tumor angiogenesis and TIMP-3 causes apoptosis, their role in cardiac angiogenesis is unknown. Interestingly, a disruption...
In this dissertation, standardized methods for measuring electron emission (EE) from nanostructured materials are established. Design of an emitter array platform, synthesis and nanomanipulation of different types of are successfully conducted....
Females have a higher incidence of autoimmune diseases than males for reasons that are currently unknown. CD4+CD25+ regulatory T cells play an important role in the maintenance of immunological homeostasis and self-tolerance by suppressing...
Background: CHF is a chronic disease that affects nearly five million people each year; in which at least 500,000 are newly diagnosed cases. Patients diagnosed with this disease will be under a physician's care for the remainder of their life. It...
Dimorphism is a highly conserved process in fungi in which a transition between a unicellular, yeast-like growth form and either a unicellular or multicellular, filamentous growth form occurs in response to several different environmental cues. The...
Background The anthracycline doxorubicin (DOX) is widely used as an effective antineoplastic drug. Cardiotoxicity leading to congestive heart failure is the primary factor limiting the clinical use of DOX. However, although a variety of approaches...
Healthy Hoops Kentucky; Asthma in children--Social aspects; Asthmatics--Social conditions
Asthma is the most common chronic disease among children aged 7 to 17 years of age in the United States. An average, one of every ten school-aged children has asthma, and 13 million school days are missed each year due to asthma. Interventions to...
Understanding of the band structure of the new nano materials is essential to have a deeper insight into their optical and electrical properties. Along with the existing techniques used for characterization of nano-materials, it is also important...
The aim of the study is to determine factors contributing to satisfaction with orthognathic surgery. It was hypothesized that specific factors contribute to the patient's perception of success. 37 patients who had orthodontic/orthognathic surgery...
Many conflicting reports have been given in the literature concerning the effect of various factors on the rate of reversal of figure and ground in reversible perspective.
Flugel (7, 8) suggested that changes in eye movement increased the number of...
The discovery of carbon nanotubes and subsequently graphene has led to an interest in carbon materials as sensing elements due to their unique properties. Graphene is a 2-dimensional material that has a large surface area that can be exposed to...
Single Walled Carbon Nanotubes (SWNTs), Double Walled Carbon nanotubes (DWNTs) and C60@SWNT (peapods) are three of well-ordered all-carbon nanostructures. Peapods are SWNTs filled with C60 fullerene peas. At high temperatues, C60 molecules coalesce...
It is to be noticed that if there be any marshy places, certain animals breed there, which are invisible to the eye and yet getting into the system through the mouth and nostrils cause serious disorders." This quaint observation is taken from...
