Research suggests that a gap exists between scholarly findings and practitioner knowledge, beliefs, and practices in the Human Resource field, particularly in the area of employee selection (Deadrick & Gibson, 2007; Rynes, Giluk, & Brown,...
Genes in folate metabolizing pathway are responsible for modulating key enzymes in folate metabolisms necessary for DNA synthesis and repair and influence DNA methylation. Irregularity in DNA methylation may modify tumor phenotype response to...
This dissertation is a hypothesis-driven research oriented study to determine the role of the pituitary-tumor transforming gene (PTTG) in ovarian cancer, specifically if it is involved in neoplastic transformation leading to tumorigenesis through...
Fatigue--Diagnosis; Reaction time--Testing; Physical fitness for women; Women athletes--Physiology
Accumulated fatigue experienced during the competitive season can be detrimental to
athletic success. The purpose of the study was to identify a performance test that best correlated
with markers of fatigue in an attempt to detect accumulated...
Spinal cord injury (SCI) can be divided into two distinct stages, an initial mechanical impact and a later "secondary injury" resulting from a cascade of cytokines triggering a spreading demyelination and apoptosis of neurons and glia...
Gold nanoparticles (AuNPs) have attracted enormous attention in the field of nanotechnology for applications such as, immunoassay, drug delivery, contrast enhancement and tumor therapy. The typical range of gold nanoparticles varies from 1– 150...
Bcl-2 proteins are major regulators of cellular responses to various apoptotic stimuli. Among them, overexpression of the anti-apoptotic BcI-2 protein BcI-xL modulates organelle-specific apoptotic pathways. To understand the mechanisms by which...
Ozone forecast models using nonlinear regression (NLR) have been successfully applied to daily ozone forecast for seven metro areas in Kentucky, including Ashland, Bowling Green, Covington, Lexington, Louisville, Owensboro, and Paducah. In this...
Background: Helicobacter pylori (Hp) establishes life-long gastric infection in billions of humans, and is often responsible for diseases such as peptic ulcer and gastric cancer. Cumulative actions of genetic drift and natural selection over...
Oxygen is critical to aerobic metabolism, but hyperoxia is cytostatic and cytocidal. The precise mechanisms involved in hyperoxic cell injury remain incompletely understood although there is substantial support for the possibility that hyperoxia...
Ground-level ozone forecast models were developed for the following middle and small metropolitan areas in Kentucky: Ashland, Bowling Green, Owensboro, and Paducah. These models were nonlinear regression models, based on models previously developed...
INTRODUCTION: Heart failure is a major and growing public health concern. Although heart failure has been considered an inexorable and progressive disorder, emerging evidence suggests that some patients may have reversible left ventricular...
Human adenoviruses (Ads) can infect and replicate in cells at different cell-cycle stages. Ads with the E1 B55K deletion preferentially replicate in cancer cells and cause oncolysis. Our laboratory has previously shown that the Ad E1 b gene is...
20S proteasome, essential component of protein degradation mechanism, is important to maintain homeostasis. Its malfunctions have been associated with several pathological conditions. This study presents an extensive study of murine cardiac 20S...
Equations of state attempt to describe the relationship between temperature (T), pressure (P), and molar volume (v) for a given substance or mixture of substances. The ideal gas law is the simplest form of an equation of state. An ideal gas can be...
Embryonic development requires the orchestration of temporally precise genetic events that culminate in the formation of a complete organism. The molecular mechanisms responsible for ontogenesis are regulated by environmental and somatic factors in...
This study compared brief, single sessions of physical activity (PA, self-paced treadmill walking) and relaxation/meditation (R/M, the "Body Scan") on positive and negative affect and anxiety measures in female undergraduates. Both were...
Teacher-student relationships; Interaction analysis in education; Problem youth--Education (Secondary)
The interactions between teachers and students provide a venue for instructional delivery and ultimately student achievement in the school setting. However, not all students experience positive interactions with teachers in the typical classroom...
Gene therapy; Spinal cord--Wounds and injuries; Tissue engineering
The combination of viral mediated gene delivery, tissue engineering, and Schwann cell (SC) transplantation offer a promising strategy to enhance axonal regeneration and functional recovery following spinal cord injury (SCI). The rationale and...
It is important to burn the air toxics and harmful gases which come from water and wastewater treatment processes. In common practice, instead of natural gas, digester gas is used for economical reasons. This burning process takes place in the...
