Inflammatory bowel disease (IBD) is a chronic autoimmune disorder that is subdivided into Crohn's disease (CD), ulcerative colitis (UC), and indeterminate colitis (IC). Epidemiological studies have proven that genetic variation increases...
Polychlorinated biphenyls (PCBs) are persistent environmental pollutants which
are detectable in the serum of all American adults. Amongst PCB congeners,
PCB 153 has the highest serum level. PCBs have been dose-dependently
associated with suspected...
Politicians' spouses; Politicians; Political campaigns
Mrs. Helen (Dillon) Mazzoli discusses her childhood and upbringing, as well as her life with Congressman Romano (Ron) Mazzoli. She describes their campaigns for office, including her own role and the ways the campaigns changed over time. She talks...
T cells; Disease susceptibility; Lupus; Sex factors in disease
Females are more susceptible to autoimmune disease than males. In several mouse models of disease, castration of males exacerbates disease while androgen treatment ameliorates disease. These data suggest hormones can have an influence on disease...
Monoclonal antibodies directed toward tumor associated antigens are FDA approved anticancer reagents used commonly in the clinic. Administered antibodies initiate tumor cell death through several mechanisms. Improving immune mediated mechanisms,...
G-quadruplexes are thought to have biological importance, with studies based on small molecule interactions and quadruplex-interactive antibodies demonstrating their potential for formation in vivo. One potential biological function of quadruplex...
School yearbooks; Schools; Students; University of Louisville--Students; Alumni & alumnae; University of Louisville--Alumni and alumnae; Student organizations; Universities & colleges; Medical students; Law students; Dental students;...
Yearbook published by the University of Louisville, Louisville, Kentucky, 1949.
Nanostructured materials; Nanotubes; Nanoparticles; Drug delivery systems; Diagnostic Imaging
Nanomaterials have many intriguing applications in biology and medicine. Unique properties such as enhanced electrical properties, increased chemical reactivity and resistance to degradation, novel optical properties and comparable size to that of...
Inflammation is now recognized as an important factor in several age-related diseases such as arthritis, atherosclerosis, multiple sclerosis and diabetes. In each case, sub-clinical chronic inflammation occurs over years and leads to progressive...
Previous studies on the mechanistic induction of anti-tumor responses by IL-12 cytokine therapy have focused on the adaptive immune response, specifically the activation NK cells and T cells as the primary targets of IL-12 treatment. In contrast,...
Inflammatory Bowel Disease (IBD) is a chronic illness with the potential to affect many areas of one's life through painful physical symptoms and psychological distress. Despite the debilitating nature and increasing prevalence of IBD, there is...
Twenty-six fossil assemblages of land and freshwater molluscs from the Pliocene to the present, were collected from locations near the town of Meade, Kansas, U.S.A. and were analyzed (along with the extant molluscan fauna of Meade County, Kansas)...
The Faroe Islands are a small archipelago in the North Atlantic. With a current population of approximately 49,000 individuals and evidence of high levels of genetic drift, the Faroese are thought to have remained highly homogeneous since their...
Parking garages--Automation; Parking garages--Design and construction
Automated vehicle storage/retrieval system (AVS/RS) technology is relatively new. It has been applied successfully in several European facilities in 1990s. AVS/RS is a flexible system that is a viable alternative to automated storage/retrieval...
This study examined the association between internalizing and externalizing symptoms, gender, and the diagnosis of Attention-Deficit/Hyperactivity Disorder. Participants included 104 males and 74 females, aged 6 to 16 from a diagnostic clinic....
Sleep disorders in children; Children--Sleep; Blind children
Research has confirmed that individuals with blindness have an increased risk of
developing sleep problems; this is especially problematic for families with young
children who are blind. Not only does the lack of sleep impact the growth...
This dissertation focuses on the mechanisms and implications of perceptual learning of binocular interactions. Perceptual learning is an important means of adapting to the changing environment, demonstrating the possibility of neural plasticity in...
School yearbooks; Schools; Students; University of Louisville--Students; Alumni & alumnae; University of Louisville--Alumni and alumnae; Student organizations; Universities & colleges; Medical students; College students; Dental students
Final monthly edition published by the students of the University of Louisville, Louisville, Kentucky, June 1922. Volume I Number 6.
This thesis will present various methods of trajectory generation for various types of mobile robots. Then it will progress to evaluating Robot Operating Systems (ROS’s) that can be used to control and simulate mobile robots, and it will explain...