Much work has been done in the past on the nutritional value in young life of different dairy products, all of which experiments have been carried to successful completion by various men at different times. There is, however, no published...
Trees in cities--Kentucky--Louisville; Urban forestry--Kentucky--Louisville; Louisville (Ky.)--Environmental conditions
Trees in urban residential neighborhoods provide valuable ecosystem services. Urban trees also face threats from disturbances, such as storms. In 2008, the Urban Forest Effects model was used to estimate abundance and species composition of...
Hip hop; Rap (Music); Alternative rock music; Geeks (Computer enthusiasts); Indie culture
In his documentary entitled, Nerdcore For Life, director Dan Lamoureux described Nerdcore as a "powerful social collision between hip hop and geek culture". Born on the Internet, Nerdcore Hip-Hop is rap music made by geeks, for geeks and...
Bartending--Technological innovations; Block diagrams; Quadratic assignment problem
Typically bartenders will arrange liquor bottles in a bar based on their own preferences. This research project describes an alternative way to arrange the bottles on the speed rail more efficiently. This will allow bartenders to make drinks...
Women's United Soccer Association; Women soccer players--History; Soccer for women; Professional sports
The purpose of this study is to examine the creation and demise of the WUSA, and to establish the league as a social movement organization (SMO) within the context of the rich body of social movement literature. In explaining the rise and fall of...
Faroe Islands; Human beings--Migrations; Human geography--Faroe Islands
The Faroe Islands are a small archipelago in the North Atlantic. With a current population of approximately 49,000 individuals and evidence of high levels of genetic drift, the Faroese are thought to have remained highly homogeneous since their...
Oxygen is critical to aerobic metabolism, but hyperoxia is cytostatic and cytocidal. The precise mechanisms involved in hyperoxic cell injury remain incompletely understood although there is substantial support for the possibility that hyperoxia...
Menthol has been regularly utilized as a treatment in sports related injuries for many years, yet little is known about its physiological interactions or its effect on performance. Our previous study indicates that topically applied menthol may...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 18. No. 35. but is actually Vol. 18. No. 36. There are tears and portions missing along the bottom...
Monoclonal antibodies directed toward tumor associated antigens are FDA approved anticancer reagents used commonly in the clinic. Administered antibodies initiate tumor cell death through several mechanisms. Improving immune mediated mechanisms,...
Chapter I . Seven novel head-to-tail cyclic pentapeptides and pseudopentapeptides containing the arginine-glycine-aspartic acid (RGD) tripeptide motif were synthesized. All of the peptides were constructed using solid phase peptide synthesis....
The fundamental question of the exact nature of the role played by TNF in the failing myocardium remains one of contention. Many preclinical studies have demonstrated beneficial effects with TNF antagonism and recently the dichotomous role played...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 32. No. 8. but is actually Vol. 33. No. 11.
Acrolein--Toxicology; Stem cells--Effect of pollution on
Acrolein is a common pollutant present in ambient air, automobile exhaust, and tobacco smoke. Previous studies show that exposure to acrolein increases cardiovascular disease risk. To determine whether acrolein affect cardiovascular regeneration,...
Na,K-ATPase is essential for the regulation of cytoplasmic Na+ and K+ levels in lens cells. Insufficient Na,K-ATPase activity is associated with cataract formation. Based on earlier studies in which Src-tyrosine kinase inhibitors were found to...
The oxidation of metallothiolates is complicated by "non-innocence" or potential
redox activity of sulfur to yield thiyl (RS•) radicals. In some instances, the one-electron
oxidation of metal thiolates yields a product with the unpaired...
T lymphopoiesis has been an intense focus of immunological research since the discovery of the major histocompatibility complex (MHC) and T cell mediated transplant rejection. Additionally, researchers have long appreciated the role of T cells, and...
The current status of our knowledge of synaptic plasticity comes largely from studies of the hippocampus and the context of learning and memory. We remain largely ignorant of plasticity in other neural systems and contexts. The molecular basis of...
Monophosphoryl Lipid A (MPLA), a derivative of LPS endotoxin, is a TLR4 agonist that displays as little as 0.1-1% as much toxicity as its parent molecule while retaining immunostimulatory properties. We discovered that MPLA activates a TRIF-biased...
Mycobacterium tuberculosis causes the often-fatal infectious disease Tuberculosis, and infects approximately one third of the world's population. Gaining a better understanding of how these bacteria regulate gene expression for intracellular...
