Dimorphism is a highly conserved process in fungi in which a transition between a unicellular, yeast-like growth form and either a unicellular or multicellular, filamentous growth form occurs in response to several different environmental cues. The...
Human arylamine N-acetyltransferase (NAT) is a phase II cytosolic enzyme that occurs as two isozymes, NAT1 and NAT2. This family of polymorphic enzymes catalyzes the detoxification and/or activation of many aromatic and heterocyclic amine drugs and...
Drug resistance in microorganisms--Mathematical models; Intensive care units
Antibiotic resistance is a problem causing growing concern in the medical community, leading some to speculate that a return to the preantibiotic era is imminent. The problem of antibiotic resistance is particularly significant in the intensive...
Outerplanar graphs are planar graphs that have a plane embedding in which each vertex lies on the boundary of the exterior region. An outerplanar graph is maximal outerplanar if the graph obtained by adding an edge is not outerplanar. Maximal...
Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) catalyze the detoxification and/or activation of aromatic and heterocyclic amine carcinogens by two pathways. This metabolism reaction can lead to the detoxification by Nacetylation, or...
Mathematical imaging consists of many different applications including image segmentation, image classification, and inpainting. This work deals more specifically with image segmentation: the partition of an image into the background and the...
Standard regularity assumptions for regression models are not satisfied in segmented regression models with an unknown change point, and consequently standard asymptotic results and inferential methods for confidence estimation are not applicable....
In the retina, the receptive fields (RFs) of most neurons are comprised of an excitatory center and a suppressive surround. Retinal ganglion cell (RGC) RF center excitatory input arises from bipolar cell (BC) inputs, while their surround arises...
The objective of this thesis is to develop computer programs for the dynamic analysis of structures. For a shear building two computer programs were developed: (1) Dynamic Analysis of a Shear Building within the Elastic Range and (2) the Dynamic...
The classification of self-dual codes has been an extremely active area in
coding theory since 1972 [33]. A particularly interesting class of self-dual codes
is those of Type II which have high minimum distance (called extremal or...
Electric power production--Data processing; Electric power distribution--Data processing
The purpose of this project was to analyze the ordering policies for a distribution system. The company has one central distribution center and nineteen branch warehouses spread throughout the country. Each branch warehouse can order product lines...
Pattern recognition systems; Cluster analysis; Data mining
Despite the large number of existing clustering methods, clustering remains a challenging task especially when the structure of the data does not correspond to easily separable categories, and when clusters vary in size, density and shape. Existing...
Given a metric space (K, d), the hyperspace of K is defined by H(K) = {F c K: F is compact, F ≠ 0}. H(K) is itself a metric space under the Hausdorff metric dH. Hyperspaces have been extensively studied by topologists since the 1970's, but the...
Equations of state attempt to describe the relationship between temperature (T), pressure (P), and molar volume (v) for a given substance or mixture of substances. The ideal gas law is the simplest form of an equation of state. An ideal gas can be...
III-nitrides (InN, GaN, AlN) are some of the most promising materials for making blue light emitting diodes (LED), blue laser diodes (LD) and high power, high temperature field effect transistors (FET). Current techniques produce GaN films with...
The purpose of this dissertation is to find ways to decrease Medicare costs and to study health outcomes of diabetes patients as well as to investigate the influence of Medicare, part D since its introduction in 2006 using the CMS CCW (Chronic...
Crossover design is a type of longitudinal study with each subject receiving different treatments in different time periods. It has been used frequently in the pharmaceutical industry and other medical fields to investigate the safety and efficacy...
Protein C (PC) is an important anticoagulant, antithrombotic, and antiinflammatory in blood plasma. PC deficiency can lead to severe venous thrombotic events, including lung embolism, stroke, and heart attack. In the body, PC is activated only when...
Three lab concrete mixes and one field concrete mix were evaluated to establish
the Air Void Analyzer (AVA) as a means of real-time, ���In-the-Field��, Quality Control
testing method. In this study, both the Air Void Analyzer and...
Mixed-effects model is an efficient tool for analyzing longitudinal data. The random effects in mixed-effects model can be used to capture the correlations among repeated measurements within a subject. The time points are not fixed and all...
