Many species of fungi undergo a dimorphic transition to switch from a unicellular yeast-like growth form to a filamentous growth form. Ustilago maydis undergoes such a transition, in response to successful mating events and subsequent host cues, to...
Dimorphism is a highly conserved process in fungi in which a transition between a unicellular, yeast-like growth form and either a unicellular or multicellular, filamentous growth form occurs in response to several different environmental cues. The...
Exocytosis of intracellular granules is critical for conversion of inactive, circulating neutrophils to fully activated cells. The p38 MAPK pathway plays a central role in neutrophil exocytosis, although its mechanism of action is unknown. We used...
The vaccinia virus complement control protein (VCP) is involved in the modulation of the host inflammatory response during vaccinia virus infection. It possesses the ability to inhibit both classical and alternative pathways of complement...
Nanoparticles; Drug delivery devices; Gene therapy
The properties and broad applications of nano-magnetic colloids have generated much interest in recent years. Specially, Fe304 nanoparticles have attracted a great deal of attention since their magnetic properties can be used for hyperthermia...
This dissertation describes research focused on the synthesis, polymerization and
applications of cationic aminooxy lipids. An efficient and convenient method was
developed to stabilize liposomes using 'click chemistry'. The 'click...
Cerium dioxide or ceria, CeO2, has been widely used in industry as catalyst for automotive exhaust controls, chemical mechanical polishing (CMP) slurries, and high temperature fuel cells because of its unique metal oxide properties. This well-known...
20S proteasome, essential component of protein degradation mechanism, is important to maintain homeostasis. Its malfunctions have been associated with several pathological conditions. This study presents an extensive study of murine cardiac 20S...
Vicinal dithioethers and alkenyl thioethers were synthesized under environmentally
friendly conditions using alkyne and thiol in water. Alkynes were also used to develop a
multibond-fonning reaction that fonned cyclic ketones or ketoesters through...
This problem originated in an attempt to make methyl glyoxal in quantity. Several methods of making methyl glyoxal are mentioned in the literature but in none of them is acetone used as a starting point. Since this seemed a new field it was decided...
Periodontitis--Treatment; Peptides--Therapeutic use
Periodontitis and its systemic sequelae remain a major public health problem and
developing a cost-efficient therapy will benefit healthcare worldwide. Adherence of
Porphyromonas gingivalis to Streptococcus gordonii facilitates colonization of the...
Archaeologists use soil analysis to detect chemicals, like phosphate, to indicate areas of anthropogenic activity. Phosphate detection is a multi-step process, which makes standard techniques time consuming. Kinetic studies decreased the analysis...
The purpose of this study was to determine the effects of acute glutamine supplementation on maximal performance and recovery from high-intensity exercise. In a placebo-controlled, crossover study, seven (six males and one female) healthy subjects...
The first effective impulse to a systematic investigation of the chemistry of food was given by Liebig some fifty years ago. The earliest quantitative analyses of food materials which we have found are those of potatoes reported by George Pearson...
In the present study, we report the synthesis of thermally stable mesoporous gallium oxide and novel gallium-niobium mixed oxides employing Evaporation Induced Self-Assembly (EISA), Self-Assembly Hydrothermal-Assisted (SAHA) and Self-Assembly...
The most important non-protein nitrogenous constituents of milk are urea, creatinine, creatine, and uric acid. Urea is the diamide of carbonic acid and is the chief end-product, so far as nitrogen is concerned, of the physiological metabolism of...
The use of monochloramines in the potable water supply industry has been selected as the disinfectant method of choice due to a longer term of effectiveness and less toxic by-products than the previous choice of chlorine. In spite of the benefits...
Electroactive polymers (EAPs), including conducting polymers (CPs) such as polyaniline (PAn), and hydrogels are exciting areas of research in disciplines such as biomedical engineering, with the goal of creating low-cost, lightweight, non-toxic...
A novel catalyst with hydro-desulfurization and hydrogenation capabilities was tested with the aim of producing ultra-low sulfur and aromatics diesel oil. The catalytically active phase is nickel in a reduced valence state on a carrier made of zinc...
Drug delivery systems; Curcumin--Therapeutic use--Administration
Curcumin, a plant derived compound has shown significant potency against various chronic diseases like cancer in cell culture and animal studies. However, the introduction of this compound into clinical setting is limited by its poor oral...
