Phase II clinical trial are generally single arm trial where a homogeneity assumption is placed on the response. In practice, this assumption may be violated resulting in a heterogeneous response. This heterogeneous or overdispersed response can be...
This study investigates the placebo effect in randomized controlled trials of low back pain. This effect has not been analyzed over time or in respect to low back pain. A meta-analysis was performed using the Pubmed/Medline database for low back...
College students--Social networks; College students--Conduct of life; Socialization
This meta-analysis draws studies from the literature on college student persistence, need theories, and positive psychology in investigating the strongest predictors of social functioning in college students in the United States and Canada. The...
Prostate cancer (PCA) development may be influenced by genetic variations within oxidative stress response (OSR) related mechanisms, such as antioxidation (e.g.,
carcinogen metabolism/detoxification), DNA repair, and apoptotic regulation. Excessive...
G-quadruplexes are thought to have biological importance, with studies based on small molecule interactions and quadruplex-interactive antibodies demonstrating their potential for formation in vivo. One potential biological function of quadruplex...
Existing treatment programs and procedures are incapable of addressing the complications encountered with patients who experience spasticity and hypertonia related joint contractures. Current passive therapy procedures and devices are only capable...
African American male college students--Social conditions; African Americans--Race identity; Academic achievement
This dissertation examines the influence of collective racial esteem (CRE) on the quantity and type of involvement for African American male undergraduate students in public four-year institutions of higher education in the U.S. In addition, this...
This dissertation explores the physical and biological factors that control zooplankton population growth rates in the Ohio River (USA). I employed both observational studies and a mesocosm experiment to ascertain zooplankton population and...
In this dissertation research, we aim to solve problems of two types of survival data, clustered survival data with potentially informative cluster size and sojourn time data. The methods for these two types of data are different. However, both...
Autism Spectrum Disorder (ASD) is an idiopathic pervasive neurodevelopmental disorder associated with various neuropathologies and immunological dysfunctions. Cytokines are regulatory proteins that facilitate communication between the immune and...
Epithelial Ovarian cancer (EOC) is the leading cause of gynecological cancer death in the USA. Recurrence rates are high after front-line platinum chemotherapy and most patients eventually die from platinum-resistant disease. P53 plays an important...
Faroe Islands; Human beings--Migrations; Human geography--Faroe Islands
The Faroe Islands are a small archipelago in the North Atlantic. With a current population of approximately 49,000 individuals and evidence of high levels of genetic drift, the Faroese are thought to have remained highly homogeneous since their...
US consumers spend $87 million annually on sporting goods and services (National Sporting Goods Association, 2008). Each year sporting goods manufacturers also spend millions of dollars creating innovative products for consumers looking to improve...
Polymorphisms in the adrenergic receptor beta-2 (ADRB2) gene have been studied in relation to risk of Type 2 diabetes and obesity, but few studies have investigated associations with breast cancer. The purpose of this research was to evaluate the...
Health--Information resources; Health--Information services; Information networks
Background: Failure to achieve their goals of over 200 U.S. Health Information Exchange Networks (HIENs) which formed or operated in the U.S. from 2004 to 2010, lost time, capital and opportunity at individual, organizational and societal levels,...
Older people--Mental health; Rural health; Urban health
Depression is one of the most prevalent psychiatric conditions experienced by older adults and represents a major public health concern. Rural/urban residence may affect the prevalence of depression as rural older adults differ from their urban...
Arrhythmia; Heart--Diseases; Heart beat; Heart conduction system
Introduction: Hyperhomocysteinemia (HHcy) is a pathological condition characterized by excessive levels of plasma homocysteine (Hcy). Patients with HHcy are reported to be at risk for arrhythmias like atrial fibrillation and sudden cardiac death...
Self-efficacy; Psychological abuse; Identity (Psychology); Women college students--Mental health
The current research proposed that psychological abuse within an intimate relationship erodes one's self-efficacy and aimed to demonstrate a negative relationship between past psychological abuse and how one reacts to a challenge. It was...
School-based management--Kentucky; Decision making
Shortly after the implementation of Kentucky's school-based decision-making councils, it became obvious that minorities were severely underrepresented on these councils. As a result, the Kentucky legislature enacted Section 160.352(3)(f) by which...
