Understanding the nucleation and early stage growth of crystals from the vapor phase is important for realizing large-area single-crystal quality films, controlled synthesis of nanocrystals, and the possible discovery of new phases of materials....
N-acetyltransferase 1 (NAT1) is a phase II metabolic enzyme responsible for the biotransformation of aromatic and heterocyclic amine carcinogens such as 4-aminobiphenyl (ASP). NAT1 catalyzes N-acetylation of arylamines as well as the 0-acetylation...
Archaeologists use soil analysis to detect chemicals, like phosphate, to indicate areas of anthropogenic activity. Phosphate detection is a multi-step process, which makes standard techniques time consuming. Kinetic studies decreased the analysis...
Zimmerman, Leo W., 1924–2008; Art, Abstract--Kentucky--Louisville; Kinetic art--Kentucky--Louisville; Mural painting and decoration, American--Kentucky--Louisville
Leo Zimmerman is a contradiction: A man who was both highly collaborative and deeply influential in the Louisville art scene but was a misanthrope who became increasingly reclusive over the years. He produced prolifically yet chose to never sell...
The oxidation of metallothiolates is complicated by "non-innocence" or potential
redox activity of sulfur to yield thiyl (RS•) radicals. In some instances, the one-electron
oxidation of metal thiolates yields a product with the unpaired...
Wind energy provides an attractive power source as an alternative to fossil fuels because it is abundant, clean, and produces no harmful emissions. To extract more energy from the wind we need to increase the wind turbine size. However, the...
Several technical and economic obstacles currently hamper the industrial development of ethanol from biomass. One of the key bottlenecks is the slow kinetics of the enzymatic hydrolysis of cellulose, and the subsequent rate reduction as the...
Ligaments--Wounds and injuries; Knee--Wounds and injuries; Women athletes--Wounds and injuries
Anterior Cruciate Ligament (ACL) injuries are among the most common injuries incurred by both recreational and professional athletes. ACL injuries often occur during popular contact sports like basketball, football, volleyball and baseball, and...
The lipid aldehydes, 4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are reactive α,β-unsaturated aldehydes generated during the peroxidation of lipids and are implicated in the pathogenesis of several oxidative-stress mediated diseases,...
More than 50% of the total energy produced is typically rejected in the form of waste heat from various processes. The grand challenge is that most of this waste heat is released at temperatures much lower than 1000 C, which makes it difficult to...
In the retina, the receptive fields (RFs) of most neurons are comprised of an excitatory center and a suppressive surround. Retinal ganglion cell (RGC) RF center excitatory input arises from bipolar cell (BC) inputs, while their surround arises...
Wind power has the potential to provide access to electricity to areas lacking the resources to create industrial power plants, as well as supplement residential energy supplies. The low resource investment and ease of installation make it ideal...
Vertical axis wind turbines (VAWTs) are devices to convert wind energy into electricity. Unlike horizontal axis wind turbines (HAWT) where the main rotor shaft is set horizontally, VAWTs use vertical rotor shaft. Unlike HAWTs, VAWTs can be...
Human arylamine N-acetyltransferase (NAT) is a phase II cytosolic enzyme that occurs as two isozymes, NAT1 and NAT2. This family of polymorphic enzymes catalyzes the detoxification and/or activation of many aromatic and heterocyclic amine drugs and...
The motivation to determine a viable alternative to petroleum based energy has risen in recent years due to increased greenhouse gas emissions, environmental pollution, and the fear of exhausting oil and natural gas reserves. Biodiesel derived from...
4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are highly reactive á,â-unsaturated aldehydes. 4-HNE and acrolein are generated in vivo as products of lipid peroxidation. These aldehydes are implicated in the onset of several diseases...
Elastomer degradation when exposed to chloraminated potable water is dependent on a number of poorly understood factors. Temperature and chloramine concentration are both believed to play roles, however, they have not been adequately defined. In...
The Knudsen pump works on the principle of thermal transpiration. As a result of requiring a thermal gradient, channel hydraulic diameter smaller than the mean free path of the gas being pumped, and having no moving parts, the Knudsen pump features...
Optimal trajectory generation is an essential part for robotic explorers to execute the total exploration of deep oceans or outer space planets while curiosity of human and technology advancements of society both require robots to search for...
Rising environmental concerns due to our rising population ad energy demand along with our excessive dependence on fossil fuels has created an urgent need to find clean, renewable and carbon free source of energy. Photoelectrochemical (PEC) water...
