Among gynecological malignancies, carcinoma of the cervix is the leading cancer type worldwide. Conversely, vaginal tumors account for an incidence of approximately 1-2% of lower genital tract malignancies. Interestingly, the major shared risk...
Griffithsin (GRFT) is a carbohydrate binding protein derived from the red alga Griffithisia sp. that has been shown to effectively interfere with the cellular attachment and infectivity of a number of viruses, including HIV-1. However, it is...
Child molesters; Child sexual abuse--Research; Child sexual abuse--Diagnosis
An exploratory cross national study was conducted to determine if factors identified in the existing literature predictive for CSA in developed countries were also valid and predictive CSA factors for females in Belize, a developing country. The...
Transcendence (Philosophy) in art; Androgyny (Psychology) in art; Jungian psychology; Art--Psychological aspects
From a Jungian perspective, this thesis investigates the ideal of androgynous transcendence by identifying the Jungian anima-animus archetype within three specific artworks produced by three differing traditions. As a result, this thesis...
Depression is one of the most frequent causes of disability worldwide. It can
affect the psychological, social, and physical wellbeing of those that suffer from it, the
majority of which are women. Depression has been linked to immune activation as...
Medical education; Medical students; Hospital College of Medicine, Louisville (Ky.)
Catalog for Hospital College of Medicine 1890. Includes faculty, program information, enrolled students 1889, graduates 1874-1889, and university information. Printed on cover: 1890. The Central University of Kentucky. Medical Department. Hospital...
Medical education; Medical students; Hospital College of Medicine, Louisville (Ky.)
Catalog for Hospital College of Medicine 1888. Includes faculty, program information, enrolled students 1887, graduates 1884-1887, and university information. Printed on cover: Announcement of the Regular Session of 1888 of the Hospital College of...
Medical education; Medical students; Hospital College of Medicine, Louisville (Ky.)
Catalog for Hospital College of Medicine 1887. Includes faculty, program information, enrolled students for 1886, graduates 1874-1886, and university information. Printed on cover: Announcement of the Regular Session of 1887 of the Hospital College...
Medical education; Medical students; Hospital College of Medicine, Louisville (Ky.)
Catalog for Hospital College of Medicine 1886. Includes faculty, program information, enrolled- students for 1885, and graduates 1874-1885. Printed on cover: Announcement of the Regular Session of 1886 of the Hospital College of Medicine Medical...
Medical education; Medical students; Hospital College of Medicine, Louisville (Ky.)
Catalog for Hospital College of Medicine 1891. Includes faculty, program information, enrolled students 1890, graduates for 1890, and university information. Printed on cover: 1891. The Central University of Kentucky, Medical Department. Hospital...
Medical education; Medical students; Hospital College of Medicine, Louisville (Ky.)
Catalog for Hospital College of Medicine 1889. Includes faculty, program information, graduates for 1888, enrolled students for 1888, and university information. Printed on cover: Hospital College of Medicine, Louisville, Kentucky. Session 1889.
T cells; Disease susceptibility; Lupus; Sex factors in disease
Females are more susceptible to autoimmune disease than males. In several mouse models of disease, castration of males exacerbates disease while androgen treatment ameliorates disease. These data suggest hormones can have an influence on disease...
Arsenic--Physiological effect; Cardiovascular system--Diseases; Liver--Effect of arsenic on; Arsenic--Toxicology
Chronic arsenic exposure is associated with increased cardiovascular disease (CVD). Prenatal arsenic exposure at 49 ppm arsenic accelerates atherosclerosis underlying CVD in ApoE-/- mice, but the mechanism is unknown. This dissertation examines the...
Mixed media textiles--Kentucky--Louisville--Exhibitions; Mixed media painting--Kentucky--Louisville--Exhibitions
My work focuses on repurposing historic images and feminine objects to create a contemporary dialogue about the traditions of courtship, marriage and divorce. The use of textiles and feminine objects such as doilies, lace, slips and wallpaper serve...
MicroRNAs (miRNAs) regulate gene expression at the post-transcriptional level by repressing translation or stimulating mRNA degradation. In this study, I tested the hypothesis that miRNAs are differentially expressed in antiestrogen-sensitive MCF-7...
Females have a higher incidence of autoimmune diseases than males for reasons that are currently unknown. CD4+CD25+ regulatory T cells play an important role in the maintenance of immunological homeostasis and self-tolerance by suppressing...
Cancer patients show circadian disruption that increases as disease progresses. Disrupted endocrine and activity rhythms predict early metastatic cancer mortality. Effects of psychological versus biological factors on rhythms are unknown, as are...