The Combinatorial Nullstellensatz can be used to solve certain problems in combinatorics. However, one of the major complications in using the Combinatorial Nullstellensatz is ensuring that there exists a nonzero monomial. This dissertation looks...
Recent advances in understanding the molecular mechanisms of mutagenesis indicate that most mutations are dependent on the activity of translesion synthesis DNA polymerases. The impact of reducing the level of these polymerases on mutagenesis and...
Many dedicated-use computer systems sold as complete products require a turn-key design delivered to the customer. This requires a system which is stable, secure, and serviceable. Adaptability of the system to existing software applications is a...
Unrepaired DNA damage poses a serious threat to the genetic stability of a replicating cell. One mechanism of tolerating this damage is translesion DNA synthesis (TLS), in which an accessory polymerase synthesizes DNA directly across from a damaged...
The Y family of DNA polymerases in higher eukaryotes contains at least four members which are implicated in potentially error-prone replication through unrepaired damage in the genome. These proteins are encoded by the REV1, POLH, POLI, and POLK...
This thesis proposes a network based intrusion detection approach using anomaly detection and achieving low configuration and maintenance costs. A honeypots is an emerging security tool that has several beneficial characteristics, one of which is...
In this dissertation, we study the performance evaluation of two automated warehouse material handling (MH) technologies - automated storage/retrieval system (AS/RS) and autonomous vehicle storage/retrieval system (AVS/RS). AS/RS is a traditional...
Exocytosis of intracellular granules is critical for conversion of inactive, circulating neutrophils to fully activated cells. The p38 MAPK pathway plays a central role in neutrophil exocytosis, although its mechanism of action is unknown. We used...
The objective of this thesis is to develop computer programs for the dynamic analysis of structures. For a shear building two computer programs were developed: (1) Dynamic Analysis of a Shear Building within the Elastic Range and (2) the Dynamic...
Influenza--United States--Management; Epidemics--Management; Health services administration; Mathematical optimization
Pandemic influenza has been an important public health concern. During the 20th century, three major pandemics of influenza occurred in 1918, 1957, and 1968. The pandemic of 1918 caused 40 to 50 million deaths worldwide and more than 500,000 deaths...
Bioinformatics; Breast--Cancer--Treatment; Medical care--Data processing
Statistical models have been the first choice for comparative effectiveness in clinical research. Though effective, these models are limited when the data to be analyzed do not fit the assumed distributions; which is mostly the case when the study...
Genes in folate metabolizing pathway are responsible for modulating key enzymes in folate metabolisms necessary for DNA synthesis and repair and influence DNA methylation. Irregularity in DNA methylation may modify tumor phenotype response to...
This research project describes the application of a master/slave configuration of processors to study a comparison of alternative material handling configurations for automated manufacturing. Such a study usually requires a large number of...
Osteoporosis has become a growing health threat with rising social and economic consequences. The understanding of the relationship between bone mechanical strength and bone structural quality is important for the diagnosis of osteoporosis and the...
Supervisory control systems--Security measures; Automatic data collection systems--Security measures; Drinking water--Security measures; Computer networks--Security measures
Supervisory control and data acquisition (SCADA) systems are used by many critical infrastructures including electric power production and distribution, water and waste water treatment, rail transportation, and gas and oil distribution. Originally...
The acetogenin annonacin, from the tropical annonaceous plant Annona muricata, is a lipophilic, mitochondrial complex I inhibitor reported to be more toxic than rotenone to mesencephalic neurons. The temperate annonaceous plant Asimina tri/oba...
The chemical analysis of atmospheric dust is of interest to two major groups, namely—the workers in industrial hygiene and the workers in the air cleaning and ventilating industries. The industrial hygienists, who are concerned with the...
Java (Computer program language); Application software--Development
The purpose of this thesis is to design, implement, and evaluate a software package that is mutli-platform and will provide software integrity management (SIM). The software package is implemented in Java and will perform two hashing algorithms,...
Grid computing is evolving as a service based, flexible and secure resource sharing environment. Currently, with the help of Grid middleware toolkits, Grids are exposing their services through programming models and command line interfaces,...
This thesis lays the groundwork for creation of a graduate-level computer forensics course. It begins with an introduction explaining how computing has invaded modern life and explains what computer forensics is and its necessity. The thesis then...
