The purpose of this study was to examine the phenomenon of teenage prescription drug abuse in Jefferson County, Kentucky to gain a better understanding of the environment and characteristics of a teenager who abuses prescription drugs, and to gain...
Masculinity--Social aspects; Drug dealers--Psychology; Male college students--Effect of stress on; Drug abuse and crime
This thesis integrates James Messerschmidt's Masculinity Theory (1997) with Robert Agnew's General Strain Theory (1992) to examine the relationship between failure to achieve ideal masculine standards, resultant psychological stressors, and the...
Drugs and crime are inextricably connected. Much of the growth in the prisoner population in America is attributable to the misuse and abuse of drugs and alcohol. Offenders who abuse or are dependent on drugs are at high risk for substantial health...
This dissertation is a post-test only comparison group study. It tests the effects of additional Motivational Interviewing sessions during the first two weeks in an intensive outpatient clinic. The object is to learn whether these additional...
Drug delivery systems; Curcumin--Therapeutic use--Administration
Curcumin, a plant derived compound has shown significant potency against various chronic diseases like cancer in cell culture and animal studies. However, the introduction of this compound into clinical setting is limited by its poor oral...
The purpose of this dissertation is to find ways to decrease Medicare costs and to study health outcomes of diabetes patients as well as to investigate the influence of Medicare, part D since its introduction in 2006 using the CMS CCW (Chronic...
Mogul Empire--Social life and customs; Drinking of alcoholic beverages--India--History; Drug abuse--India
Intoxicant use in Mughal India was not only widespread, it also represented an important part of the empire's history and culture. The influence of intoxicants - specifically opium and alcohol - has often been overlooked in secondary literature,...
Discrimination in criminal justice administration--United States; Drug control--Social aspects--United States; War on Terrorism, 2001- --Social aspects; Crime and race--United States; United States--Race relations
This thesis is an examination of the relationship between race and ethnicity and the American justice system. It is a comparative case study of the racial dimensions of the War on Drugs in the domestic criminal justice system and the ethnic...
Drug resistance in microorganisms--Mathematical models; Intensive care units
Antibiotic resistance is a problem causing growing concern in the medical community, leading some to speculate that a return to the preantibiotic era is imminent. The problem of antibiotic resistance is particularly significant in the intensive...
Prostate--Cancer--Diagnosis; Chemical detectors; Biosensors
Prostate cancer is the most common type diagnosed among men in the United States.
Random oligodeoxynucleotide (ODN) libraries are used to generate DNA aptamers by
systematic evolution of ligands by exponential enrichment (SELEX). We explored...
The vast knowledge of nucleic acids is evolving and it is now known that DNA can adopt highly complex, heterogeneous structures. Among the most intriguing are the G-quadruplex structures, which are thought to play a pivotal role in cancer...
Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease with poor prognosis.
To address this disease broadly, the candidate engaged in clinical work, literature
analysis, database analysis, and laboratory work. The clinical work culminated...
Inflammation is now recognized as an important factor in several age-related diseases such as arthritis, atherosclerosis, multiple sclerosis and diabetes. In each case, sub-clinical chronic inflammation occurs over years and leads to progressive...
Parkinson's disease--Treatment; Stem cells--Therapeutic use
Parkinson's disease (PD) is a hypokinetic movement disorder resulting from the
progressive neurodegeneration of the dopaminergic nigrostriatal system in the brain and
the resulting imbalance between dopamine and acetylcholine in the basal ganglia...
Chapter I . Seven novel head-to-tail cyclic pentapeptides and pseudopentapeptides containing the arginine-glycine-aspartic acid (RGD) tripeptide motif were synthesized. All of the peptides were constructed using solid phase peptide synthesis....
Osteoporosis has become a growing health threat with rising social and economic consequences. The understanding of the relationship between bone mechanical strength and bone structural quality is important for the diagnosis of osteoporosis and the...
The study purpose was three-fold: finding a point of entry for primary prevention of child neglect, assessing for child neglect risk level for both first-time mothers and their partners, and individuals opinions about establishing and administering...
c-Myc dysregulation is one of the most common abnormalities found in human cancer. MicroRNAs (miRNAs) are functionally intertwined with the c-Myc network as multiple miRNAs are regulated by c-Myc, while others directly suppress c-Myc expression. In...
Self-control in children; Crime and race; Parent and teenager; Teenagers--Family relationships
This study seeks to examine whether racial disparities in offending can be explained through self-control theory. The study utilized longitudinal responses of a nationally representative sample of 1700 adolescents. Parenting and self-control...
