Mucin 1 (MUC1) is a plasma membrane-bound glycoprotein that plays a protective role in corneal epithelial cells. Two full-length splice variants of MUCl: MUCl/B and MUCl/A, that differ by the inclusion of 27 bp from intron 1 and a SNP in MUCl/A,...
Through differential display PCR, Munc13-3 was identified as a gene whose relative expression in the visual cortex corresponds to critical period plasticity. Expression of the gene was low at the peak of the critical period and expression was high...
This dissertation focuses on the mechanisms and implications of perceptual learning of binocular interactions. Perceptual learning is an important means of adapting to the changing environment, demonstrating the possibility of neural plasticity in...
Age-related macular degeneration (ARMD) and retinitis pigmentosa (RP) are the two leading causes of blindness in the world today. Despite enormous efforts and advances in clinical treatment of eye diseases, there is no established method or cure of...
This work examines our perception of distance within "action space" (about 2m ~ 30m), an ability that is important for various actions. Two general problems are addressed: what information can be used to judge distance accurately and how...
The goals of this dissertation is to further the understanding of the roles of two genes identified by differential display polymerase chain reaction (ddPCR) of cat visual cortex as candidate genes to play a role in visual cortical plasticity....
This thesis and exhibition examine the connection between neurobiology and Op Art. Neurobiological explanations of Op Art's effects are explored as a means to offer insight into the processes of the human mind and eye, and to provide explanations...
Plague--History--Europe; Black Death--Social aspects--Europe; Erotica--Europe--History; Idols and images--Europe--History; Superstition--Europe--History
This thesis examines a large corpus of enigmatic pilgrimage badges dating from
roughly 1350-1500 CE. The badges were brought to light during archaeological
excavations of water sites throughout the Schelde Estuary in the Netherlands, the
riverbanks...
Down syndrome--Patients; Williams syndrome--Patients; Social interaction in children; Social perception in children
The present project examined the regulatory function of social referencing in two neurodevelopmental disorders that have been well defined genetically and are characterized by differing patterns of socio-cognitive development: Down syndrome (DS)...
Shakespeare, William, 1564-1616; Courtly love in literature
"It is in the south of France and at a very early period that we must look for the origin of the system of Courtly Love. Gathered about several small courts, there existed, as early as the eleventh century, a brilliant society, in which woman...
Neuropsychology; Motor ability; Eye-hand coordination
Two major theoretical models, Direct Mapping and Functional Equivalence, suggest that the observation of action and imagery of action, respectively, involve activation of similar motor related areas. Despite the wealth of evidence that supports...
Hyaluronan (HA) is a major structural component of the ocular vitreous humor
(VH) and lipids are essential building blocks of cell membranes. However, little is known
about their possible interactions. The VH is known to undergo liquefaction...
Museum exhibits; Art--Study and teaching (Elementary); Color in art
Color is an important part of art and life, which can be utilized by the museum educator to engage visitors with the art. For the museum educator, development of appropriate programs and activities to meet the needs of their audience is a central...
Buildings; University of Louisville--Buildings; Research facilities;
Kentucky Lions Eye Research Institute, main entrance. The building has a prominent roof structure overhanging the entrance. Location: Health Sciences Campus: 301 East Muhammad Ali Boulevard. Current uses: Ophthalmology and Visual Sciences...
Buildings; University of Louisville--Buildings; Research facilities; Bird's-eye views; Cityscape photographs; Cityscapes;
Birds-eye view of the Kentucky Lions Eye Research Institute. The roof of the entrance way overhang reflects in the gold mirrored glass on the front of the building. The Louisville cityscape surrounds the building. Location: Health Sciences Campus:...
Na,K-ATPase is essential for the regulation of cytoplasmic Na+ and K+ levels in lens cells. Insufficient Na,K-ATPase activity is associated with cataract formation. Based on earlier studies in which Src-tyrosine kinase inhibitors were found to...
The process of designing the settings and lighting for a show is an adventure; it's a story that has the normal components of any good story, a beginning, middle and end. There is tension, conflict, climax and resolution. It contains characters who...
While democracy was developing, while men were seeking to reform national politics and to find some means by which the people might be represented justly in the government, a new movement entered into literature to give it a broadened scope and a...
Sociology, Urban--California--Los Angeles; Urbanization--California--Los Angeles; Ontology--Social aspects; Social epistemology
Noir Ontology: Existing in the Fragmented Urban Spaces of Los Angeles explores the role of decentered urban geography within the body of noir texts set within Los Angeles. By focusing on the development of the idea of Los Angeles in early to...
Congenital stationary night blindness 1 (CSNBl) is a genetic disorder characterized in humans by night blindness, low visual acuity and myopia. CSNB 1 is caused by defects in genes that are involved in signaling between photoreceptors and...