Genes in folate metabolizing pathway are responsible for modulating key enzymes in folate metabolisms necessary for DNA synthesis and repair and influence DNA methylation. Irregularity in DNA methylation may modify tumor phenotype response to...
Influenza--United States--Management; Epidemics--Management; Health services administration; Mathematical optimization
Pandemic influenza has been an important public health concern. During the 20th century, three major pandemics of influenza occurred in 1918, 1957, and 1968. The pandemic of 1918 caused 40 to 50 million deaths worldwide and more than 500,000 deaths...
This dissertation is composed of three essays in which I examine the influence of formal institutions on entrepreneurs and new firms. In the first essay, "The Influence of Institutions on the Likelihood of Self-Employment: A Multilevel...
Data mining; Lungs--Cancer; Outcome assessment (Medical care)
Lung cancer is the leading cause of cancer death in the United States and the world, with more than 1.3 million deaths worldwide per year. However, because of a lack of effective tools to diagnose Lung Cancer, more than half of all cases are...
Funeral rites and ceremonies--United States; Undertakers and undertaking--Social aspects
Within a cultural context of postmodernism and individualization, funerals in America have taken on a new appearance amidst increased freedom of expression and diminished adherence to tradition. This thesis examines how the funeral industry has...
Mogul Empire--Social life and customs; Drinking of alcoholic beverages--India--History; Drug abuse--India
Intoxicant use in Mughal India was not only widespread, it also represented an important part of the empire's history and culture. The influence of intoxicants - specifically opium and alcohol - has often been overlooked in secondary literature,...
Prints; Screen prints; Allusions; Death; Disasters; Tragedies; Accidents; Automobiles; Vehicles; Dead persons; Wounds & injuries; Voyeurism; Social aspects; Social classes
"The use of serial repetition here, as in other early Warhol works, relates interestingly to Minimalist uses of repetition. The reciprocally ironic relation between Warhol and the Minimalists came to a head in 1964. Warhol exhibited a series...
From a computerized image analysis prospective, early diagnosis of lung cancer involves detection of doubtful nodules and classification into different pathologies. The detection stage involves a detection approach, usually by template matching,...
Coronary heart disease--Treatment--Cost effectiveness; Angioplasty; Medical laws and legislation--Kentucky
A myocardial infarction (MI) occurs when blood supply to the heart is cut off by a blockage in one of the coronary arteries. Most hospitals treat a patient with thrombolysis or a percutaneous coronary intervention (PC I). The latter has been...
It has been estimated that 30% of all cancer deaths in the U.S. are associated with obesity. It is well-established that obesity promotes low-grade chronic inflammation, however the mechanisms by which obesity-induced chronic inflammation may...
Persecution--England--History--16th century; Martyrdom--Christianity--England; Great Britain--History--Elizabeth, 1558-1603; Great Britain--History--Mary, 1553-1558
This thesis is a historical examination of the Marian and Elizabethan persecutions. Through the analysis of primary sources dating from the persecutions, the process of persecution in Reformation England is examined. This thesis uncovers the...
Polycyclic aromatic hydrocarbons; Fetus--Effect of tobacco on
Polycyclic aromatic hydrocarbons (PAH) are chemicals generated from the incomplete combustion of organic materials, including tobacco smoke. Some PAH are known to be mutagenic and carcinogenic in humans, and of concern for the fetus when women...
Psychic trauma in art; Psychoanalysis and art; Art--Psychological aspects; Salomon, Charlotte, 1917-1943. Leben oder theater?
This thesis explores the presence of the dialectic of trauma in Charlotte Salomon’s magnum opus, Life? or Theatre?, a series of more than seven hundred paintings created during her time in exile in France between 1941 and 1942. In this series,...
Green tea--Health aspects; Green tea--Therapeutic use; Polyphenols--Physiological effect; Drug delivery systems; Lungs--Cancer--Treatment
Green tea polyphenols (GTPs) are gaining increasing attention because of their potential anti-tumor effects. However, poor oral bioavailability limits their efficacy in vivo. In this dissertation, two hypotheses were tested: 1) GTPs administered...
Acrolein--Toxicology; Stem cells--Effect of pollution on
Acrolein is a common pollutant present in ambient air, automobile exhaust, and tobacco smoke. Previous studies show that exposure to acrolein increases cardiovascular disease risk. To determine whether acrolein affect cardiovascular regeneration,...
Three-dimensional imaging in medicine; Lungs--Cancer--Diagnosis
Many lung diseases or injuries can cause biomechanical or material property changes that can alter
lung function. While the mechanical changes associated with the change of the material properties
originate at a regional level, they remain largely...
Discrimination in criminal justice administration--United States; Drug control--Social aspects--United States; War on Terrorism, 2001- --Social aspects; Crime and race--United States; United States--Race relations
This thesis is an examination of the relationship between race and ethnicity and the American justice system. It is a comparative case study of the racial dimensions of the War on Drugs in the domestic criminal justice system and the ethnic...
Infants--Wounds and injuries; Falls (Accidents); Neck--Wounds and injuries; Head--Wounds and injuries
The purpose of this study was to determine the risk of severe head and neck injury in short distance falls for a 12-month-old child. A series of free falls and falls from standing were experimentally simulated using an instrumented anthropomorphic...
Background . Heart failure treatment guidelines emphasize the importance of daily weight monitoring. To support this practice, the Health Care Financing Administration Heart Failure Demonstration Project (2000) was designed to evaluate the effect...
