The vast knowledge of nucleic acids is evolving and it is now known that DNA can adopt highly complex, heterogeneous structures. Among the most intriguing are the G-quadruplex structures, which are thought to play a pivotal role in cancer...
In blood coagulation, the serine protease thrombin is a multifaceted enzyme that interacts with multiple proteins. Thrombin utilizes two anion binding exosites (ABE-I and II) to supplement binding to fibrinogen and to the platelet receptor GpIbα,...
This dissertation describes new procedures for synthesizing and purifying Au and Au/Ag nanoplates directly on surfaces as well as controlled binding of proteins to their surface. It also describes fundamental changes in the optical properties of Au...
BACKGROUND: Regulated secretion of protein by salivary and other exocrine glands requires correct trafficking of soluble cargo proteins into secretory vesicles. However, the molecular mechanism of sorting in the parotid salivary gland is unknown....
It has been estimated that 30% of all cancer deaths in the U.S. are associated with obesity. It is well-established that obesity promotes low-grade chronic inflammation, however the mechanisms by which obesity-induced chronic inflammation may...
The current status of our knowledge of synaptic plasticity comes largely from studies of the hippocampus and the context of learning and memory. We remain largely ignorant of plasticity in other neural systems and contexts. The molecular basis of...
This thesis reports the reactivity of the rhenium-thiolate complex, tris(2-diphenylphosphinobenzenethiolato)rhenium(III), [Re(DPPBT) 3 ] ( 1 ) and its oxidized derivatives with ethylene. The reactivity has been studied by electrochemical,...
Sculpture; Men; Athletes; People associated with entertainment & sports; Nudes; Genitals; Muscles; Clothing & dress; Capes (Clothing); Headbands (Headgear); Headgear; Victories; Tree stumps; Trees; Archaeological sites; Ruins; Expedition...
Supported by two workers from Mykonos. “Island marble. Found in the building known conventionally as the House of the Diadoumenos, on Delos, in 1894. The hands are missing. The tip of the nose is restored. The youth is depicted nude, frontally,...
