The chaperone heat shock protein 90 (Hsp90) regulates physiologically and
pathological cellular processes, by binding and stabilizing kinases involved in basal
cellular functions and in cellular responses to stress, respectively. I hypothesize...
Within the Appalachian hills of eastern Kentucky, large-scale coal mining operations are directly altering the headwater landscape through the construction of hollow fills. These man-made landforms and their associated in-stream structures alter a...
We are more likely to "hurt the one's we love" than we are complete strangers (cf. R. Miller, 1991, 1997). Early in dating relationships, partners appear to me more likely to manage their impressions to present themselves as better than...
In the United States substance abuse takes a toll that is costly in both economic and human terms. In 2005 we paid 467.7 billion dollars to address the consequences of substance abuse, and each year we have lost an estimated 537,000 of our fellows...
African American students--Education; Mathematics--Study and teaching (Elementary); Academic achievement--Psychological aspects; Stereotypes (Social psychology)
African American students continue to underperform and are underrepresented in areas, including mathematics (Heubert & Hauser, 1999; Jencks & Phillips, 1998; National Postsecondary Education Cooperative, Gandara, Bial, & Educational...
Senile dementia; Nursing home patients--Mental health; Anxiety in old age; Depression in old age
Dementia, depression, and anxiety are the most common psychiatric disorders among long-term care residents and, because dementia is associated with behavioral problems that can be difficult to manage, the growing number of long-term care residents...
US consumers spend $87 million annually on sporting goods and services (National Sporting Goods Association, 2008). Each year sporting goods manufacturers also spend millions of dollars creating innovative products for consumers looking to improve...
Professional ethics does not differ in its essential nature from general ethics; both are concerned with problems of human conduct. The difference between the two is a difference of scope but not of nature. The scope of general ethics is as broad...
Older people--Mental health; Philosophy of mind; Cognitive science--Health aspects
Declines in social resources and in the quality of interpersonal interactions have been observed in some older adults. Unawareness of ability is a clinical problem that has been found in some older adults with dementia, but has also been found in...
Teachers of children with disabilities--Attitudes; Mainstreaming in education; Students with disabilities
This dissertation is an examination of general education teacher's attitudes toward the inclusion of students with special needs in their classroom and the variables that influence these attitudes. A theoretical framework for the examination of...
Computer music; Sound--Recording and reproducing--Digital techniques; Music and technology; Computer sound processing
This thesis proposes a concept called low-time-resolution (LTR) structure in music, and investigates its potential significance and application in music-related computing tasks.
The contributions of the thesis are manifold. First, it proposes a...
Income distribution; Occupational training--Economic aspects; Academic achievement--Economic aspects
Employing a two-stage least-squares multiple regression technique using cross-sectional data from metropolitan statistical areas (MSAs) as the unit of analysis, this study is designed to detect the indirect effect of skill-biased technological...
Inflammatory Bowel Disease (IBD) is a chronic illness with the potential to affect many areas of one's life through painful physical symptoms and psychological distress. Despite the debilitating nature and increasing prevalence of IBD, there is...
Capital punishment--Public opinion; Murder victims' families--Attitudes; Murder victims' families--Psychology
Two common assumptions are that the family members of murder victims will achieve closure and perceive a sense of justice following the execution of their loved one's murderer. These assumptions, however, may be unfounded. Using family member...
INTRODUCTION: Heart failure is a major and growing public health concern. Although heart failure has been considered an inexorable and progressive disorder, emerging evidence suggests that some patients may have reversible left ventricular...
Conducting polymers; Polymers in medicine; Myocardium
Hydrophilic and conductive characteristics in polymers are mutually exclusive of each other. Hydrophilic polymer properties allow absorption of water up to several magnitudes above their dry weight. However, due to their molecular structure, they...
Prostate--Cancer--Diagnosis; Chemical detectors; Biosensors
Prostate cancer is the most common type diagnosed among men in the United States.
Random oligodeoxynucleotide (ODN) libraries are used to generate DNA aptamers by
systematic evolution of ligands by exponential enrichment (SELEX). We explored...
An individual's role set consists of a variety of different roles (Biddle, 1979; Madsen & Hammond, 2005). Parent, spouse, student, and even sports fan, all constitute roles within one's role set. Fulfilling role demands requires time, energy,...
The purpose of the research is to assess the emergency communication messages that water and wastewater utilities used to correspond with the public during a crisis event. This assessment includes a review of data and disseminated messages provided...
The Adoption and Safe Families Act created specific outcomes for permanency for children in foster care. The purpose of these outcomes is to decrease the number of children in long term foster care. Seven years have passed since ASFA was signed...
