The revolution in information technology and the explosion in the use of computing devices in people's everyday activities has forever changed the perspective of the data mining and machine learning fields. The enormous amounts of easily...
Cortical and tectal inputs to the caudal LPN in the rat were examined using anatomical and physiological techniques. Pyramidal cells in layer 6 of the visual cortex and wide-field vertical cells in the stratum opticum of the superior colliculus...
The pulvinar is the largest nucleus of the human dorsal thalamus and is affected in a variety of brain disorders, such as schizophrenia. The experiments described in this dissertation elucidate key features of tecto-pulvino-cortical pathways as a...
T cells; Disease susceptibility; Lupus; Sex factors in disease
Females are more susceptible to autoimmune disease than males. In several mouse models of disease, castration of males exacerbates disease while androgen treatment ameliorates disease. These data suggest hormones can have an influence on disease...
Reperfusion of the ischemic lung causes pulmonary arteriolar vasoconstriction and reduces alveolar perfusion. Lung ischemia-reperfusion (IR) injury leads to platelet and leukocyte activation which could contribute to decreased alveolar perfusion...
Females have a higher incidence of autoimmune diseases than males for reasons that are currently unknown. CD4+CD25+ regulatory T cells play an important role in the maintenance of immunological homeostasis and self-tolerance by suppressing...
Outerplanar graphs are planar graphs that have a plane embedding in which each vertex lies on the boundary of the exterior region. An outerplanar graph is maximal outerplanar if the graph obtained by adding an edge is not outerplanar. Maximal...
The secondary visual pathway, from the retina through the superior colliculus and pulvinar nucleus has been linked to spatial attention (Snow et aI., 2009; Arend et aI., 2008) movement planning and motor response to visual stimuli (Wilke et aI....
To manage large image databases, Content-Based Image Retrieval (CBIR) emerged as a new research subject. CBIR involves the development of automated methods to use visual features in searching and retrieving. Unfortunately, the performance of most...
While investigating estrogen response element (ERE) binding properties of Erα in de-identified human breast cancer extracts, additional proteins were observed that recognized ERE sequences (ERE-BP). In order to unravel the apparent role of these...
The term "promiscuity" is often used in academic literature and pejoratively
proliferated among society at large. The definition of promiscuity has not been clearly
and consistently defined within research and varies significantly from...
The vaccinia virus complement control protein (VCP) is involved in the modulation of the host inflammatory response during vaccinia virus infection. It possesses the ability to inhibit both classical and alternative pathways of complement...
The goals of this dissertation is to further the understanding of the roles of two genes identified by differential display polymerase chain reaction (ddPCR) of cat visual cortex as candidate genes to play a role in visual cortical plasticity....
This dissertation addresses two different problems: 1) coronal loop detection from solar images: and 2) salient contour group extraction from cluttered images. In the first part, we propose two different solutions to the coronal loop detection...
Emergency management--Kentucky; Assistance in emergencies--Kentucky; Disaster relief--Kentucky; Transportation--Planning
Large-scale emergencies caused by earthquake, tornado, pandemic flu, terrorism attacks and so on can wreak havoc to communities. In order to mitigate the impact of the events, emergency stockpiles of food, water, medicine and other materials have...
The inherited bone marrow failure syndromes (IBMFS) encompass a heterogeneous collection of rare disorders characterized by hematological abnormalities, generalized growth delays, and an increased incidence of malignant transformation. These...
Collateral sprouting (CS) occurs when uninjured axons respond to denervated tissue surrounding the axon by growing branches of the axon to reinnervate the denervated zone. This process is signaled by factors released by the denervated tissue. Nerve...
Nanomaterials have many intriguing applications in biology and medicine. Unique properties such as enhanced electrical properties, increased chemical reactivity and resistance to degradation, novel optical properties and comparable size to that of...
The website has become a staple in the business environment, to provide information and services, and connect business-to-business and business-to-customers. Many of these sites require re-engineering in order to facilitate the needed complexities...
The advent of larger storage spaces, affordable digital capturing devices, and an ever growing online community dedicated to sharing images has created a great need for efficient analysis methods. In fact, analyzing images for the purpose of...