Three lab concrete mixes and one field concrete mix were evaluated to establish
the Air Void Analyzer (AVA) as a means of real-time, ���In-the-Field��, Quality Control
testing method. In this study, both the Air Void Analyzer and...
Long-term exposure to harmful carcinogens like benzo[a]pyrene (BaP) are linked to lung cancer. Benzo[a]pyrene diol epoxide (BPDE), the ultimate carcinogen produced by BaP bioactivation, is believed to play an important role in lung carcinogenesis....
Epithelial Ovarian cancer (EOC) is the leading cause of gynecological cancer death in the USA. Recurrence rates are high after front-line platinum chemotherapy and most patients eventually die from platinum-resistant disease. P53 plays an important...
The classification of self-dual codes has been an extremely active area in
coding theory since 1972 [33]. A particularly interesting class of self-dual codes
is those of Type II which have high minimum distance (called extremal or...
Alcohol; Distillation; Alcoholic beverages; Corn--Utilization; Whiskey industry
In the whisky industry there is a balance between the desire to adhere to the traditional production process and the desire to increase profit margins. One solution that follows both stipulations is to increase the alcohol yield of a given batch of...
Microhotplates for metal oxide gas sensors are fabricated using platinum microheaters and tested. Power consumption is monitored and temperature distributions are observed using infrared microscopy. Temperature line traces are extracted from the...
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
Trees in cities--Kentucky--Louisville; Urban forestry--Kentucky--Louisville; Louisville (Ky.)--Environmental conditions
Trees in urban residential neighborhoods provide valuable ecosystem services. Urban trees also face threats from disturbances, such as storms. In 2008, the Urban Forest Effects model was used to estimate abundance and species composition of...
Bartending--Technological innovations; Block diagrams; Quadratic assignment problem
Typically bartenders will arrange liquor bottles in a bar based on their own preferences. This research project describes an alternative way to arrange the bottles on the speed rail more efficiently. This will allow bartenders to make drinks...
A blinded observational cross-sectional in vitro study was conducted to compare the diagnostic accuracy of observers viewing images made using cone beam computerized tomography (CBCT), panoramic radiography and linear tomography. The sample...
Rising concerns about dependency on fossil fuels in the 21st century has sparked a growth in research for renewable energy sources. One renewable energy production process of interest is the reduction of cellulose into fermentable sugars by means...
Water treatment facilities strive to provide potable drinking water to the community which they service. The most common way of insuring drinkable water that is free of pathogens is water chlorination, but this can lead to the production of...
This dissertation is a hypothesis-driven research oriented study to determine the role of the pituitary-tumor transforming gene (PTTG) in ovarian cancer, specifically if it is involved in neoplastic transformation leading to tumorigenesis through...
Pituitary tumor transforming gene ( PTTG ), also known as securing, is a novel oncogene that is expressed at high levels in most of the tumors analyzed to date. Overexpression of PTTG in mouse fibroblast(NIH 3T3) cells increases cell proliferation,...
Arsenic--Physiological effect; Cardiovascular system--Diseases; Liver--Effect of arsenic on; Arsenic--Toxicology
Chronic arsenic exposure is associated with increased cardiovascular disease (CVD). Prenatal arsenic exposure at 49 ppm arsenic accelerates atherosclerosis underlying CVD in ApoE-/- mice, but the mechanism is unknown. This dissertation examines the...
Drug resistance in microorganisms; Salmonella typhimurium
Salmonella enterica serovar Typhimurium is an enteric pathogen capable of infecting
a wide range of hosts. The manner in which this pathogen is able to interact with its
host is difficult to define, as is the case with most microbes. Through the...
Among gynecological malignancies, carcinoma of the cervix is the leading cancer type worldwide. Conversely, vaginal tumors account for an incidence of approximately 1-2% of lower genital tract malignancies. Interestingly, the major shared risk...
Cerium dioxide or ceria, CeO2, has been widely used in industry as catalyst for automotive exhaust controls, chemical mechanical polishing (CMP) slurries, and high temperature fuel cells because of its unique metal oxide properties. This well-known...
Bcl-2 proteins are major regulators of cellular responses to various apoptotic stimuli. Among them, overexpression of the anti-apoptotic BcI-2 protein BcI-xL modulates organelle-specific apoptotic pathways. To understand the mechanisms by which...
DNA microarrays--Statistical methods; Gene expression--Statistical methods
Data derived from gene expression microarrays are frequently used to identify candidate genes which can characterize and distinguish between two biological phenotypes. A key step in this process is the selection of an appropriate test statistic to...
