Pituitary tumor transforming gene ( PTTG ), also known as securing, is a novel oncogene that is expressed at high levels in most of the tumors analyzed to date. Overexpression of PTTG in mouse fibroblast(NIH 3T3) cells increases cell proliferation,...
Skeletal muscle is the most abundant tissue in our body that provides a structural framework and regulates important biological processes. It is also a primary reservoir of protein. Skeletal muscle maintains its structural and functional integrity...
Metastasis is a complex process requiring directed migration of metastatic cells to favorable microenvironments. Increased CXCR4 expression has been implicated in more invasive, aggressive and metastatic tumor phenotypes and poor patient survival...
In blood coagulation, the serine protease thrombin is a multifaceted enzyme that interacts with multiple proteins. Thrombin utilizes two anion binding exosites (ABE-I and II) to supplement binding to fibrinogen and to the platelet receptor GpIbα,...
A potential source of fine grained suspended sediments in a stream system is the
upper hillslopes of the drainage. Quantifying the sediment produced and transported to a
stream from these hillslopes is challenging because of the complex nature of...
Characterization of the optical and electrical properties of organic solar cell materials is of prime importance to organic solar cell design. This thesis describes the use of capacitive photocurrent measurements to study the exciton generation and...
Hospital care--Computer simulation; Hospitals--Computer simulation; Medical appointments and schedules
With more and more attention surrounding healthcare, Industrial Engineers have championed the task to help hospitals and outpatient centers operate as efficiently as possible. Simulation is often used to analyze hospital performance measures. The...
Among gynecological malignancies, carcinoma of the cervix is the leading cancer type worldwide. Conversely, vaginal tumors account for an incidence of approximately 1-2% of lower genital tract malignancies. Interestingly, the major shared risk...
It has been estimated that 30% of all cancer deaths in the U.S. are associated with obesity. It is well-established that obesity promotes low-grade chronic inflammation, however the mechanisms by which obesity-induced chronic inflammation may...
4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are highly reactive á,â-unsaturated aldehydes. 4-HNE and acrolein are generated in vivo as products of lipid peroxidation. These aldehydes are implicated in the onset of several diseases...
African American families--Mental health; Parenting--Psychological aspects; Anxiety
To investigate the effects of anxiety and ethnicity on parental control as well as the effects ethnicity, anxiety, and parental control have on child diagnostic severity, anxious African American and Caucasian families were compared. Sixty-nine...
Grading and marking (Students)--Data processing; Discourse analysis--Data processing; Instructional systems--Design
In recent years the use of Tablet PCs in education has received a great deal of attention. Improved note-taking and lecture presentation have been the main focus of Tablet PCs in education. Currently, grading of student work collected as digital...
Children with disabilities--Education (Secondary); Vocabulary--Study and teaching (Secondary); Mathematics--Study and teaching (Secondary)
Constant Time Delay (CST) has been used extensively as a procedure to teach children with disabilities a variety of skills. There is a preponderance of evidence that this instructional strategy is a highly effective (Handen & Zane, 1987;...
Computer-assisted instruction; Three-dimensional imaging; Neuroanatomy--Study and teaching (Higher)
Visualizations in the form of computer-based learning environments are highly
encouraged in science education, especially for teaching spatial material. Some spatial
material, such as sectional neuroanatomy, is very challenging to learn. It...
Vicinal dithioethers and alkenyl thioethers were synthesized under environmentally
friendly conditions using alkyne and thiol in water. Alkynes were also used to develop a
multibond-fonning reaction that fonned cyclic ketones or ketoesters through...
Lung cancer is the deadliest type of known cancer in the United States, claiming hundreds of thousands of lives each year. However, despite the high mortality rate, the 5-year survival rate after resection of Stage 1A non–small cell lung cancer...
Nanostructured materials; Nanotubes; Nanoparticles; Drug delivery systems; Diagnostic Imaging
Nanomaterials have many intriguing applications in biology and medicine. Unique properties such as enhanced electrical properties, increased chemical reactivity and resistance to degradation, novel optical properties and comparable size to that of...
In order to satisfy customer expectations, a ground vehicle must be designed to meet a broad range of performance requirements. A satisfactory vehicle design process implements a set of requirements reflecting necessary, but perhaps not sufficient...
Iron oxide, Fe2O3, is a promising material for water splitting reaction using solar
energy due to its stability and optimal bandgap of 2 eV. Even the recent efforts, however,
using Fe2O3 thin film materials reported low efficiencies due to poor...
