Epithelial Ovarian cancer (EOC) is the leading cause of gynecological cancer death in the USA. Recurrence rates are high after front-line platinum chemotherapy and most patients eventually die from platinum-resistant disease. P53 plays an important...
Health--Information resources; Health--Information services; Information networks
Background: Failure to achieve their goals of over 200 U.S. Health Information Exchange Networks (HIENs) which formed or operated in the U.S. from 2004 to 2010, lost time, capital and opportunity at individual, organizational and societal levels,...
Xenoestrogens are spread throughout the environment affecting our daily
lives and may produce potential toxic effects on human health. The purpose of
this study was to develop a mechanistically reliable model capable of identifying
xenoestrogens....
Urbanization disrupts natural soil profiles and as watersheds are
urbanized, their surfaces become impervious and this will result in
reduction of infiltration. For this reason, many cities are facing problems
with treating runoff water. Best...
Current high-throughput gene expression experiments have a straightforward design of examining
the gene expression of one group or condition relative to that of another. The data is typically
analyzed as if they represent strictly intracellular...
High-throughput sequencing has provided a myriad of genetic data for thousands of organisms. Computational analysis of one data type, expressed sequence tags (ESTs) yields insight into gene expression, alternative splicing, tissue specificity gene...
Emergency medicine--Diagnosis; Emergency medical services
A retrospective study involving the secondary analysis of public health surveillance records was undertaken to characterize the reliability and validity of an EMS dispatch data-based scheme for assigning emergency patients to surveillance syndromes...
Online organizations are always in search for innovative marketing strategies to better satisfy their current website users and lure new ones. Thus, recently, many organizations have started to retain all transactions taking place on their website,...
Remote terminal units (RTUs) are perimeter supervisory control and data acquisition (SCADA) devices that measure and control actual physical devices. Cyber security was largely ignored in SCADA for many years, and the cyber security issues that now...
Java (Computer program language); Application software--Development
The purpose of this thesis is to design, implement, and evaluate a software package that is mutli-platform and will provide software integrity management (SIM). The software package is implemented in Java and will perform two hashing algorithms,...
This thesis proposes a network based intrusion detection approach using anomaly detection and achieving low configuration and maintenance costs. A honeypots is an emerging security tool that has several beneficial characteristics, one of which is...
Since the beginning of the VLSI era, various technologies have been adopted for developing the design and characterization of analog circuits. For robust design, the influences of the process parameter variations have been considered over the...
This thesis begins by reviewing human N-acetyltransferases (Chapter I), then outlines experiments involving human hepatocytes and rat N-acetyltransferases (Chapters II-V). These experiments facilitated the development of a dissertation project...
This thesis lays the groundwork for creation of a graduate-level computer forensics course. It begins with an introduction explaining how computing has invaded modern life and explains what computer forensics is and its necessity. The thesis then...
A combination of three techniques – high resolution micro computed tomography (micro CT) scanning, Archimedes-based volume fraction measurement and serial sectioning or milling – were used to determine the volume fraction, trabecular thickness,...
In order to study the movements of autonomous mobile robots, a tool is needed to quantify those movements. A testbed is an apparatus that provides a designated space for multiple mobile robots while tracking their position in real-time. That...
Nuclear magnetic resonance spectroscopy; Spectrum analysis--Data processing
Since its development, nuclear magnetic resonance (NMR) has become one of the primary methods of chemists for structure elucidation, which is the determination of a compound's molecular structure. Current software packages enable scientists to...
The purpose of this research study is to examine the use of time series forecasting and text mining to investigate the prescription of antibiotics. The specific objective is to examine the relationship between the total payments, private insurance...
Ozone forecast models using nonlinear regression (NLR) have been successfully applied to daily ozone forecast for seven metro areas in Kentucky, including Ashland, Bowling Green, Covington, Lexington, Louisville, Owensboro, and Paducah. In this...
