Several technical and economic obstacles currently hamper the industrial development of ethanol from biomass. One of the key bottlenecks is the slow kinetics of the enzymatic hydrolysis of cellulose, and the subsequent rate reduction as the...
Integration of the Internet with a Cellular Network, WMAN, WLAN, and MANET presents an exceptional promise by having co-existence of conventional WWANs/WMANs/WLANs with wireless ad hoc networks to provide ubiquitous communication. We call such...
Introduction: Autism is a complex developmental disability that typically appears during
the first three years of life, and is the result of a neurological disorder that affects the
normal functioning of the brain, impacting development in the...
Cardiology--Research--Methodology; Microfluidics--Equipment and supplies
Cardiovascular disease (CVD) is the leading cause of death in the United States and accounts for nearly 1,372,000 deaths each year. In addition, ~81 million Americans suffer from some form of CVD. Understanding the molecular basis of various...
In the electronic and microfabrication industry, die separation is one of the most critical steps in producing an undamaged, stand-alone micro-scale device. For silicon based devices, it is the predominant step governing resistance to die failure...
It is to be noticed that if there be any marshy places, certain animals breed there, which are invisible to the eye and yet getting into the system through the mouth and nostrils cause serious disorders." This quaint observation is taken from...
The ability of L. pneumophila to cause disease depends on its replication in alveolar macrophages. Infectivity and the expression of various virulence traits is triggered at post exponential growth phase. We show that unlike quiescent macrophages,...
Background - Cranial cruciate ligament (CrCL) rupture in the canine stifle is a leading
cause of orthopedic lameness in the dog. Several corrective surgical procedures have
been developed to return dogs to pre-injury function following CrCL...
Evidence suggests that cortical minicolumns are reduced in size and increased in number in individuals with autism spectrum disorder (ASD), especially in the dorsolateral prefrontal cortex (DLPFC). More specifically minicolumns in individuals with...
Heart failure is the most frequent cause of mortality in western countries. Currently, there is no cure treatment for heart failure and the long term survival rate following heart failure is poor, with one third of patients dying within a year of...
Cancer accounts for nearly one-quarter of deaths in the United States, exceeded only by heart diseases. Despite the development of various strategies to treat cancer, it remains one of the most deadly diseases worldwide due to the limited effects...
Monophosphoryl Lipid A (MPLA), a derivative of LPS endotoxin, is a TLR4 agonist that displays as little as 0.1-1% as much toxicity as its parent molecule while retaining immunostimulatory properties. We discovered that MPLA activates a TRIF-biased...
Colorectal cancer is the fourth most common cancer, and the fourth leading cause of cancer related death in the United States. It also happens to be one of the most preventable cancers provided an individual performs a regular screening. For years...
Athletic shoes; Foot--Wounds and injuries--Prevention
The purpose of this investigation was to determine if cycling shoes made with stiff material cause an increase in peak plantar stress over shoes with less stiff material. Shoe stiffness measurements were collected under controlled conditions and in...
Protein C (PC) is an important anticoagulant, antithrombotic, and antiinflammatory in blood plasma. PC deficiency can lead to severe venous thrombotic events, including lung embolism, stroke, and heart attack. In the body, PC is activated only when...
Respiratory syncytial virus is the leading cause of lower respiratory tract infection
in infants and currently lacks an effective vaccine or treatment beyond symptom relief.
The atomic force microscope is particularly well suited for imaging...
The leading cause of death in the United States is cardiovascular disease, a result of atherosclerosis. The reducing agent N-(2-Mercaptopropionyl)glycine (MPG) as been found to be an effective antioxidant therapy in a number of conditions, and our...
Supervisory Control and Data Acquisition (SCADA) systems are used in almost
all industrial processes including use in the nation's critical infrastructure. The electric,
water, and gas industries are merely a few that rely heavily on the use of...
Pancreatic adenocarcinoma is the fourth leading cause of cancer death in the United States. It is identified by its rapid, invasive progression with a profound resistance to treatments such as chemotherapy. Unfortunately, there is a lack of...
Hemolysis, the major cause for specimen rejection in clinical laboratories is defined as the rupture of red blood cell membranes, resulting in the release of hemoglobin into the plasma. Blood flow in needles causes hemolysis resulting in...
