Autism Spectrum Disorder (ASD) is an idiopathic pervasive neurodevelopmental disorder associated with various neuropathologies and immunological dysfunctions. Cytokines are regulatory proteins that facilitate communication between the immune and...
Embryonic development requires the orchestration of temporally precise genetic events that culminate in the formation of a complete organism. The molecular mechanisms responsible for ontogenesis are regulated by environmental and somatic factors in...
College students--Attitudes; College dropouts; Dropout behavior, Prediction of; Academic achievement; Prediction of scholastic success
This study explored the relationship between engagement in educationally purposeful activities during the first year of college and academic achievement, persistence, and graduation. The study focused on the impacts of engagement on student...
Acrolein--Toxicology; Stem cells--Effect of pollution on
Acrolein is a common pollutant present in ambient air, automobile exhaust, and tobacco smoke. Previous studies show that exposure to acrolein increases cardiovascular disease risk. To determine whether acrolein affect cardiovascular regeneration,...
Tick-borne diseases; Health behavior; Health attitudes; Health education--Social aspects
Human monocytic ehrlichiosis (HME), a tick-borne disease that has recently surfaced in
the United States, exists in regions where the tick vector population is established. This
study utilizes methods that look beyond identifying high-risk regions,...
Child maltreatment touches almost 700,000 children annually. The effects
of child maltreatment range from micro-level consequences, such as behavior
problems and mental health issues, to mezzo-level consequences, such as
increased child...
Adjustment (Psychology) in old age; Aging; Elderly poor; Nursing home patients
BACKGROUND: Current successful aging theory excludes individuals with disease or
disability, limits the potential for successful aging in minority and lower socioeconomic
populations, focuses on behavioral determinants of health rather than social...
Long-term exposure to harmful carcinogens like benzo[a]pyrene (BaP) are linked to lung cancer. Benzo[a]pyrene diol epoxide (BPDE), the ultimate carcinogen produced by BaP bioactivation, is believed to play an important role in lung carcinogenesis....
Inflammatory bowel disease (IBD) is a chronic autoimmune disorder that is subdivided into Crohn's disease (CD), ulcerative colitis (UC), and indeterminate colitis (IC). Epidemiological studies have proven that genetic variation increases...
In 2003, Wilson Creek running through Bernheim Arboretum and Research Forest in central Kentucky was restored to its original winding path through a valley field. Early 20th century settlers had previously redirected this creek to run a straight...
Intelligent transportation systems; Air quality; Air--Pollution
Environmental or air quality impacts of Intelligent Transportation Systems (ITS)
are very difficult to measure. Some researchers have attempted to quantify the effects of
individual ITS application on emissions; yet, the effects of ITS as a whole...
N-acetyltransferase 1 (NAT1) is a phase II metabolic enzyme responsible for the biotransformation of aromatic and heterocyclic amine carcinogens such as 4-aminobiphenyl (ASP). NAT1 catalyzes N-acetylation of arylamines as well as the 0-acetylation...
Tobacco smoke is a strong and independent risk factor for several chronic systemic diseases and also increases susceptibility to a multitude of bacterial infections, including periodontal infections. Periodontitis is a chronic inflammatory disease...
This dissertation is an investigation of the influence of individual characteristics and school climate on the participation in deviant behaviors. The literature review provides a review of adolescent development and theories that guide the...
Several technical and economic obstacles currently hamper the industrial development of ethanol from biomass. One of the key bottlenecks is the slow kinetics of the enzymatic hydrolysis of cellulose, and the subsequent rate reduction as the...
College dropouts--Indiana; Educational attainment--Indiana; College freshmen--Indiana; Community college students--Indiana
The purpose of this exploratory study was to determine if student background variables (age, gender, race, academic preparation); student status (part/full-time student), and student circumstances (commuting distance, independent/dependent...
Health--Information resources; Health--Information services; Information networks
Background: Failure to achieve their goals of over 200 U.S. Health Information Exchange Networks (HIENs) which formed or operated in the U.S. from 2004 to 2010, lost time, capital and opportunity at individual, organizational and societal levels,...
This dissertation explores the physical and biological factors that control zooplankton population growth rates in the Ohio River (USA). I employed both observational studies and a mesocosm experiment to ascertain zooplankton population and...
Water treatment facilities strive to provide potable drinking water to the community which they service. The most common way of insuring drinkable water that is free of pathogens is water chlorination, but this can lead to the production of...
Dimorphism is a highly conserved process in fungi in which a transition between a unicellular, yeast-like growth form and either a unicellular or multicellular, filamentous growth form occurs in response to several different environmental cues. The...