Mucin 1 (MUC1) is a plasma membrane-bound glycoprotein that plays a protective role in corneal epithelial cells. Two full-length splice variants of MUCl: MUCl/B and MUCl/A, that differ by the inclusion of 27 bp from intron 1 and a SNP in MUCl/A,...
Previous studies on the mechanistic induction of anti-tumor responses by IL-12 cytokine therapy have focused on the adaptive immune response, specifically the activation NK cells and T cells as the primary targets of IL-12 treatment. In contrast,...
Nazi Saboteurs Trial, Washington, D.C., 1942; Trials (Sabotage)--Washington (D.C.); War and emergency powers--United States; Military courts--United States--History
For over two hundred years a major issue in the history of the United States is the contentious issue of military commissions. Military commissions are not new or specific to the United States, but the United States traces its first military...
Gene therapy; Spinal cord--Wounds and injuries; Tissue engineering
The combination of viral mediated gene delivery, tissue engineering, and Schwann cell (SC) transplantation offer a promising strategy to enhance axonal regeneration and functional recovery following spinal cord injury (SCI). The rationale and...
Nanoparticles; Imaging systems in medicine; Imaging systems in biology
Gold nanoparticles (GNPs) have shown beneficial properties for biomedical use, e.g., their non-toxic nature and surface properties for easy modification. Upon receiving light, they generate a strong surface plasmon field, which can alter the...
Regression analysis is a statistical method used to relate a variable of interest, typically y (the dependent variable), to a set of independent variables, usually, X1, X2,...,Xn . The goal is to build a model that assists statisticians in...
Among gynecological malignancies, carcinoma of the cervix is the leading cancer type worldwide. Conversely, vaginal tumors account for an incidence of approximately 1-2% of lower genital tract malignancies. Interestingly, the major shared risk...
"Regen-Kanon" is the fourth of six pieces or "sound images" in the orchestral cycle Spharen, composed by York Holler between 2001 and 2006. The first four movements, namely "Wolkengesang" ("Song of the...
This thesis is an examination and analysis of the role of law enforcement in the transformation of a city's downtown from one dominated by sleazy strip bars and prostitutes to one of family entertainment. The focus is on the police and prosecutors;...
Tallis, Thomas, ca. 1505-1585. Lamentations, no. 1; Tallis, Thomas, ca. 1505-1585. Lamentations, no. 2; Byrd, William, 1542 or 3-1623. De Lamentatione Hieremiae;
Movement through pitch space in the Common Practice Period is generally acknowledged as being structured on the fifth relation, whereas movement through the pitch space of the highly chromatic music of the nineteenth century is thought of as being...
Teachers--Job satisfaction--Kentucky--Louisville; Teacher turnover--Kentucky--Louisville; First year teachers--Kentucky--Louisville
This study addressed the job satisfaction of new teachers in Jefferson County Public Schools (JCPS). in Jefferson County, Kentucky. The JCPS district is the 29th largest in the United Sates and serves over 98,000 students. Understanding what...
The research problem presented herein involved the
structural determination of several a,~-unsaturated acids
and esters. The solution to this problem was sought in the
nuclear magnetic resonance (n.m.r.) spectra of these compounds.
The n.m.r....
The works of Maurice Duruflé (1902-1986) comprise a small but significant body of sacred music and compositions for organ, yet they have received little serious analytical attention. The present study examines an early organ work, the Prélude,...
It is not the primary purpose of this present work to treat the problem of the evolution of behavior, but rather to give an analysis of animal behavior as observed. These observations may appear as simple tests, but they make possible a new way to...
Kentucky--Governor (1859-1862 : Magoffin); Kentucky--History--Civil War, 1861-1865; United States--History--Civil War, 1861-1865
This thesis seeks to understand Beriah Magoffin as Governor of Kentucky. Adding to the work begun by Michael T. Dues and Lowell H. Harrison during the 1960s and 1970s, this thesis fleshes out a man little studied in history. It addresses several...
General. – The Characaeae is the only extant family of an ancient and unique group of nonvascular aquatic plants which are classified as a separate division, the Charophyta (Groves and Bullock-Webster, 1920; Zaneveld, 1940; Imahori, 1954; Bold,...
Hypoxia is characterized by an inadequate oxygen supply to the tissues in
proportion to their metabolic needs, and is a primary factor in traumatic CNS
injury, strokes, cardiopulmonary diseases, and obstructive sleep apnea. The
cAMP-dependent...
Standard regularity assumptions for regression models are not satisfied in segmented regression models with an unknown change point, and consequently standard asymptotic results and inferential methods for confidence estimation are not applicable....
Parkinson's disease--Treatment; Stem cells--Therapeutic use
Parkinson's disease (PD) is a hypokinetic movement disorder resulting from the
progressive neurodegeneration of the dopaminergic nigrostriatal system in the brain and
the resulting imbalance between dopamine and acetylcholine in the basal ganglia...
The purpose of this study was to determine the effects of acute glutamine supplementation on maximal performance and recovery from high-intensity exercise. In a placebo-controlled, crossover study, seven (six males and one female) healthy subjects...
