As more attention is focused toward carbon dioxide emissions into the environment, conversion of CO2 to useful chemicals can utilize the extra carbon dioxide captured from power plant stack gas, instead of sequestration. The mainstream method of...
Characterization of the optical and electrical properties of organic solar cell materials is of prime importance to organic solar cell design. This thesis describes the use of capacitive photocurrent measurements to study the exciton generation and...
Periodontitis is a chronic, destructive inflammatory disease of the supporting
tissues of the teeth with a high prevalence among adults. While the complete
pathogenesis of periodontitis remains unclear, it is initiated and sustained by...
Nitrile hydratase (NHase) is a metalloenzyme that contains a non-heme iron (III)
or non-corin cobalt (III) in a non-redox active role. NHase is used as biocatalyst in the
industry for the hydrolysis of nitriles to arnides. The trivalent metal ions...
Prostate--Cancer--Diagnosis; Chemical detectors; Biosensors
Prostate cancer is the most common type diagnosed among men in the United States.
Random oligodeoxynucleotide (ODN) libraries are used to generate DNA aptamers by
systematic evolution of ligands by exponential enrichment (SELEX). We explored...
Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease with poor prognosis.
To address this disease broadly, the candidate engaged in clinical work, literature
analysis, database analysis, and laboratory work. The clinical work culminated...
Current high-throughput gene expression experiments have a straightforward design of examining
the gene expression of one group or condition relative to that of another. The data is typically
analyzed as if they represent strictly intracellular...
Gas manufacture and works; Carbon dioxide mitigation; Natural gas
The separation of carbon dioxide from natural gas is of great interest from the environmental and energy perspective, respectively. From the environmental point of view, capturing CO2 effectively from power plants can have a positive impact on...
Very little is known about the acridine ring system. Such compounds as acriflavine, brucine and strychnine are generally believed to contain the acridine ring system. These compounds are all very important drugs. Acriflavine has been used in the...
In the bulk of experiments on animal feeding the Albino Rat has served as the experimental animal. It has been proved that any diet which brings about satisfactory growth in white rats will also cause a young child to grow satisfactorily....
It is not the primary purpose of this present work to treat the problem of the evolution of behavior, but rather to give an analysis of animal behavior as observed. These observations may appear as simple tests, but they make possible a new way to...
English literature--Early modern, 1500-1700; Geographical discoveries in literature
It is the purpose of this thesis to show what influence the sixteenth century voyagers had on the Elizabethan writers. For expediency, we have divided these voyages into two classes: namely, the early, from Columbus, 1492, to Vasca de Gama, 1498;...
Periodontitis; Iron--Health aspects; Iron in the body
The dental pathogen A. actinomycetemcomitans, a Gram- negative organism, has been associated with aggressive forms of periodontitis. A. actinomycetemcomitans requires iron to grow. In the host, iron-binding proteins such as transferrin,...
Background. Progression of alcoholic liver disease (ALD) is associated with an increase in fibrin extracellular matrix (ECM) and inflammation. Previous studies have shown that this accumulation of fibrin in ALD is mediated by impaired fibrinolysis....
The objective of my dissertation research was to determine the role of chemical signals in conveying information regarding an individual's health status and suitability as a mate in humans and to examine the role that commensal microflora play in...
Hemolysis, the major cause for specimen rejection in clinical laboratories is defined as the rupture of red blood cell membranes, resulting in the release of hemoglobin into the plasma. Blood flow in needles causes hemolysis resulting in...
Embryonic development requires the orchestration of temporally precise genetic events that culminate in the formation of a complete organism. The molecular mechanisms responsible for ontogenesis are regulated by environmental and somatic factors in...
Chapter I . Seven novel head-to-tail cyclic pentapeptides and pseudopentapeptides containing the arginine-glycine-aspartic acid (RGD) tripeptide motif were synthesized. All of the peptides were constructed using solid phase peptide synthesis....
Spinal cord injury (SCI) can be divided into two distinct stages, an initial mechanical impact and a later "secondary injury" resulting from a cascade of cytokines triggering a spreading demyelination and apoptosis of neurons and glia...
Diabetic cardiomyopathy (DCM) is a common complication leading to accelerated cardiovascular failure in diabetic patients. Even though the exact mechanism(s) behind this disease still remain unclear, research from several laboratories including our...
