Aims. The primary aim of this study was to compare esthetic outcomes for the Nobel Replace Standard implant vs. the Nobel Perfect Scalloped implant as determined by hard and soft tissue measurements and objective and subjective esthetic indices....
Dentists--Attitudes; Endodontics--Study and teaching; Medical referral
The decision by a general dentist to treat or refer a patient needing endodontic therapy may be based on multiple variables. Students attending dental schools with endodontic specialty programs could be exposed to a referral system with endodontic...
Emergency medicine--Diagnosis; Emergency medical services
A retrospective study involving the secondary analysis of public health surveillance records was undertaken to characterize the reliability and validity of an EMS dispatch data-based scheme for assigning emergency patients to surveillance syndromes...
Coronary heart disease--Treatment--Cost effectiveness; Angioplasty; Medical laws and legislation--Kentucky
A myocardial infarction (MI) occurs when blood supply to the heart is cut off by a blockage in one of the coronary arteries. Most hospitals treat a patient with thrombolysis or a percutaneous coronary intervention (PC I). The latter has been...
A common research interest in medical, biological, and engineering research is determining whether certain independent variables are correlated with the survival or failure times. Standard statistical techniques cannot usually be applied for...
Bioinformatics; Breast--Cancer--Treatment; Medical care--Data processing
Statistical models have been the first choice for comparative effectiveness in clinical research. Though effective, these models are limited when the data to be analyzed do not fit the assumed distributions; which is mostly the case when the study...
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
Historically in the area of pediatric heart failure, few options have been available that are specifically designed to provide pediatric circulatory support. Extracorporeal Membrane Oxygenation (ECMO) was the traditional method of choice, providing...
Aims. The primary aims of this randomized, controlled, blinded clinical trial were to compare the hard and soft tissue response following either a connective tissue (CT) or acellular dermal matrix (ADM) graft placed simultaneously with a...
When Howard Manning wakes from a fainting spell to find himself hospitalized with a serious but correctable weakness in his heart, his refusal of treatment intimates a death wish that provokes consternation among the skilled medical professionals...
Medical care--Decision making; Decision making--Simulation methods
A variety of methodologies have been employed for decision making related to the treatment of diseases/injury. Decision trees are a functional way in which to examine problems under uncertainty by providing a method to analyze decisions under risk...
Aims. The primary aims of this randomized, controlled, blinded clinical trial were to
compare the hard and soft tissue response following either a connective tissue (CT) or
acellular dermal matrix (ADM) graft placed...
The past decade has brought about major advances in the realms of both
healthcare and biometrics. New technologies and techniques in the field of biometrics
has allowed for the quick and efficient identification of people, while new...
Background: Emerging circulatory support devices that operate in counterpulsation to the native heart require synchronized timing of device ejection and filling on a beat-to-beat basis with the native heart using a patient's ECG. Surface leads are...
Lung cancer is the deadliest type of known cancer in the United States, claiming hundreds of thousands of lives each year. However, despite the high mortality rate, the 5-year survival rate after resection of Stage 1A non–small cell lung cancer...
Dermal wounds, including bed sores, pressure ulcers, and diabetic ulcers have a large impact on American healthcare costing up to $7 billion per year. Adequate pharmaceutical remedies applied at constant rate could prove to increase the healing...
Circulating nucleated cell populations found in whole blood, including both white blood cells (leukocytes) and endothelial cells, provide an ideal platform for studies seeking to understand the disease processes for development of drugs and...
While investigating estrogen response element (ERE) binding properties of Erα in de-identified human breast cancer extracts, additional proteins were observed that recognized ERE sequences (ERE-BP). In order to unravel the apparent role of these...
Cancer accounts for nearly one-quarter of deaths in the United States, exceeded only by heart diseases. Despite the development of various strategies to treat cancer, it remains one of the most deadly diseases worldwide due to the limited effects...
INTRODUCTION: Attention Deficit/Hyperactivity Disorder (ADHD) is a disorder that is prevalent throughout the world. It is believed that 5% of school aged children suffer from ADHD, with some estimates indicating as high as 10% may suffer from the...