The ability of L. pneumophila to cause disease depends on its replication in alveolar macrophages. Infectivity and the expression of various virulence traits is triggered at post exponential growth phase. We show that unlike quiescent macrophages,...
New products--Management; Consumer satisfaction; Marketing--Management
A constant flow of innovative products which meets the needs of customers and therefore is a monetary success for the inventing organization is important for the long term success of organizations, especially in modem dynamic markets. As resources...
Micro air vehicles (MAVs) are type of unmanned aircraft with a maximum length of 150 mm (6 in.) and flight speed of less than 10 m/s. Because their flight speed is comparable to the environmental wind speed coupled with their small size and low...
Heuristic; Production management; Personnel management--Data processing
The Naval Surface Warfare Center wishes to create a task assignment schedule
with a minimal training cost for workers to raise their skills to the required levels. As the
number of workers, skills, and tasks increase, the problem quickly becomes...
The role of the active site tyrosine residue in the Co-C5' bond activation in the
context of adenosylcobalamin-dependent mutases has been computationally
investigated. The density functional, complete active space self-consistent field
and quantum...
Chapter 1 detailed the synthesis method of hydroxamate peptides derivatives of pentapeptide Ac-PHSXX\'-N-NH2 by solid phase hydroxamate peptide synthesis method. The glutamic acid/aspartic acid side chain was modified to hydroxamic acid by on resin...
Self-efficacy; Psychological abuse; Identity (Psychology); Women college students--Mental health
The current research proposed that psychological abuse within an intimate relationship erodes one's self-efficacy and aimed to demonstrate a negative relationship between past psychological abuse and how one reacts to a challenge. It was...
Urinary incontinence is a major public health problem affecting 30% of community dwelling women aged 35-85. Urinary incontinence may have a significant impact on activities of daily living depending on the severity of symptoms. Women with urinary...
Unrepaired DNA damage poses a serious threat to the genetic stability of a replicating cell. One mechanism of tolerating this damage is translesion DNA synthesis (TLS), in which an accessory polymerase synthesizes DNA directly across from a damaged...
4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are highly reactive á,â-unsaturated aldehydes. 4-HNE and acrolein are generated in vivo as products of lipid peroxidation. These aldehydes are implicated in the onset of several diseases...
Sex offenders--Psychology; Sex offenders--Research
Based primarily on theory, it is suspected that violent and non-violent sex-offenders can be differentiated by their psychopathic profile, as measured by the Psychopathy Checklist-Revised (PCL-R; Hare, 1991). There is some concern that current...
Orbital shakers are commonly used in the cell culture industry due to their ease of use, but the fluid dynamics of this system have not been extensively modeled as the system is difficult to quantify analytically. It is desirable to understand how...
Heart--Hypertrophy; Hydrogen sulfide--Therapeutic use
Background: Although matrix metalloproteinase (MMPs) and tissue inhibitor of metalloproteinase (TIMPs) play a vital role in tumor angiogenesis and TIMP-3 causes apoptosis, their role in cardiac angiogenesis is unknown. Interestingly, a disruption...
Crystalline beta-Ga2O3 nanowires with two distinct morphologies have been synthesized through simple physical evaporation of Te doped GaAs powder in argon atmosphere. The structure of the nanowires was characterized by SEM, TEM, XRD, EDX, and raman...
In the present study, we report the synthesis of thermally stable mesoporous gallium oxide and novel gallium-niobium mixed oxides employing Evaporation Induced Self-Assembly (EISA), Self-Assembly Hydrothermal-Assisted (SAHA) and Self-Assembly...
The facility layout problem is a combinatorial optimization problem that involves determining the location and shape of various departments within a facility based on inter-department volume and distance measures. An optimal solution to the problem...
Cardiology--Research--Methodology; Microfluidics--Equipment and supplies
Cardiovascular disease (CVD) is the leading cause of death in the United States and accounts for nearly 1,372,000 deaths each year. In addition, ~81 million Americans suffer from some form of CVD. Understanding the molecular basis of various...
The separation of C02 from light gases is a very important environmental and energy issue. The state-of-the-art process for the purification of C02 uses amine adsorption, which is a complex, and costly. Membrane technology is far less expensive...
High solids processing of biomass slurries provides the following benefits: maximized product concentration in the fermentable sugar stream, reduced water usage, and reduced reactor size. However, high solids processing poses mixing and heat...
III-nitrides (InN, GaN, AlN) are some of the most promising materials for making blue light emitting diodes (LED), blue laser diodes (LD) and high power, high temperature field effect transistors (FET). Current techniques produce GaN films with...
